iPTMnet Report for Q9NYB9 (ABI2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9NYB9 / ABI2_HUMAN
Protein Name Abl interactor 2
Gene Name Name: ABI2
Synonyms:ARGBPIA;
Organism Homo sapiens (Human)

PRO ID PR:Q9NYB9
DAG View
PRO Name Abl interactor 2 (human)
Definition An Abl interactor 2 that is encoded in the genome of human.
Short Label hABI2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9NYB9 (ABI2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K43 Ubiquitination PhosphoSitePlus
S88 Phosphorylation PhosphoSitePlus
K123 Ubiquitination PhosphoSitePlus
K139 Ubiquitination PhosphoSitePlus
K167 Ubiquitination PhosphoSitePlus
T174 Phosphorylation PhosphoSitePlus
T175 Phosphorylation PhosphoSitePlus
T178 Phosphorylation PhosphoSitePlus
S183 Phosphorylation PRO   PhosphoSitePlus   UniProt 23186163
S187 Phosphorylation PhosphoSitePlus
T191 Phosphorylation PhosphoSitePlus
S196 Phosphorylation PhosphoSitePlus
Y198 Phosphorylation PhosphoSitePlus
T200 Phosphorylation PhosphoSitePlus
R205 Methylation PhosphoSitePlus
Y213 Phosphorylation PhosphoSitePlus
S216 O-Glycosylation GlyGen 31373491
S216 Phosphorylation phospho.ELM   PRO   PhosphoSitePlus 18669648
T218 O-Glycosylation GlyGen 31373491
T218 Phosphorylation PhosphoSitePlus
S224 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S227 Phosphorylation phospho.ELM   PRO   PhosphoSitePlus   UniProt 18669648, 23186163, 21406692, ...20068231
R230 Methylation PhosphoSitePlus
T231 Phosphorylation PhosphoSitePlus
S233 Phosphorylation PhosphoSitePlus
T240 Phosphorylation PhosphoSitePlus
Y241 Phosphorylation PhosphoSitePlus
S242 Phosphorylation PhosphoSitePlus
S244 Phosphorylation PhosphoSitePlus
S253 Phosphorylation PhosphoSitePlus
T361 O-Glycosylation GlyGen 30379171, 35254053
T361 Phosphorylation PhosphoSitePlus
T364 O-Glycosylation GlyGen 31373491
T364 Phosphorylation PhosphoSitePlus
S368 O-Glycosylation GlyGen 31373491
S368 Phosphorylation PhosphoSitePlus   UniProt 23186163, 20068231
Y371 Phosphorylation PhosphoSitePlus
S376 Phosphorylation PhosphoSitePlus
S416 Phosphorylation PRO
Y460 Phosphorylation PhosphoSitePlus
T463 Phosphorylation PhosphoSitePlus
K466 Acetylation PhosphoSitePlus
K482 Acetylation PhosphoSitePlus
S512 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
K154 Ubiquitination PhosphoSitePlus
Y207 Phosphorylation PhosphoSitePlus
S210 Phosphorylation HPRD 18669648
S218 Phosphorylation HPRD 18669648, 19415658, 20068231
S221 Phosphorylation HPRD 17322306, 19651622, 18669648, ...19664994, 20068231
S236 Phosphorylation PhosphoSitePlus
S271 Phosphorylation PhosphoSitePlus
S274 Phosphorylation PhosphoSitePlus
Y284 Phosphorylation HPRD   PhosphoSitePlus 20068231
S285 Phosphorylation PhosphoSitePlus
R288 Methylation PhosphoSitePlus
T294 Phosphorylation HPRD 20068231
T297 Phosphorylation HPRD 20068231
S301 Phosphorylation HPRD 20068231
Y304 Phosphorylation PhosphoSitePlus


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000046225 (hABI2/Phos:1) pS183,pS216,pS227,pS416 PRO


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T294 A294 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S301 T301 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S301 W301 Biomuta DOID:363 / uterine cancer [ cosmic ]