Protein Information

Cytoscape View

UniProt AC / UniProt ID Q9NY59 / NSMA2_HUMAN
Protein Name Sphingomyelin phosphodiesterase 3
Gene Name Name: SMPD3
Organism Homo sapiens (Human)

DAG View
PRO Name sphingomyelin phosphodiesterase 3 (human)
Definition A sphingomyelin phosphodiesterase 3 that is encoded in the genome of human.
Short Label hSMPD3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

Q9NY59 (SMPD3) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
S203 Phosphorylation PhosphoSitePlus
S209 Phosphorylation PhosphoSitePlus
T279 Phosphorylation PhosphoSitePlus
S291 Phosphorylation PhosphoSitePlus   UniProt 24275569
S328 Phosphorylation PhosphoSitePlus
K435 Ubiquitination PhosphoSitePlus

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S209 F209 Biomuta DOID:3571 / liver cancer [ tcga ]
S328 L328 Biomuta DOID:3070 / malignant glioma [ tcga ]