iPTMnet Report for Q9NY59 (SMPD3)
Protein Information
| UniProt AC / UniProt ID | Q9NY59 / NSMA2_HUMAN |
| Protein Name | Sphingomyelin phosphodiesterase 3 |
| Gene Name | Name: SMPD3 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9NY59 |
| PRO Name | sphingomyelin phosphodiesterase 3 (human) |
| Definition | A sphingomyelin phosphodiesterase 3 that is encoded in the genome of human. |
| Short Label | hSMPD3 |
| Category | organism-gene |
DAG ViewQ9NY59 (SMPD3) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| K103 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S203 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S209 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y212 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T279 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S291 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
| S328 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K435 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S209 | F209 | Biomuta | DOID:4159 / skin cancer [ cosmic ] DOID:4606 / bile duct cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic, icgc ] | |
| S328 | L328 | Biomuta | DOID:1319 / brain cancer [ icgc ] |
