Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9NY46 / SCN3A_HUMAN
Protein Name Sodium channel protein type 3 subunit alpha
Gene Name Name: SCN3A
Synonyms:KIAA1356,NAC3;
Organism Homo sapiens (Human)

PRO ID PR:Q9NY46
DAG View
PRO Name sodium channel protein type 3 subunit alpha (human)
Definition A sodium channel protein type 3 subunit alpha that is encoded in the genome of human.
Short Label hSCN3A
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9NY46 (SCN3A) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K33 Acetylation PhosphoSitePlus
S466 Phosphorylation PhosphoSitePlus
S473 Phosphorylation PhosphoSitePlus
S484 Phosphorylation PhosphoSitePlus
S485 Phosphorylation PhosphoSitePlus
S489 Phosphorylation PhosphoSitePlus
S493 Phosphorylation PhosphoSitePlus
S535 Phosphorylation PhosphoSitePlus
S536 Phosphorylation PhosphoSitePlus
S554 Phosphorylation PhosphoSitePlus
S568 Phosphorylation PhosphoSitePlus
S573 Phosphorylation PhosphoSitePlus
S576 Phosphorylation PhosphoSitePlus
S610 Phosphorylation PhosphoSitePlus
S707 Phosphorylation PhosphoSitePlus
T715 Phosphorylation PhosphoSitePlus
S842 Phosphorylation PhosphoSitePlus
S848 Phosphorylation PhosphoSitePlus
S852 Phosphorylation PhosphoSitePlus
K1028 Ubiquitination PhosphoSitePlus
T1157 Phosphorylation PhosphoSitePlus
K1491 Acetylation PhosphoSitePlus
S1559 Phosphorylation PhosphoSitePlus
T1570 Phosphorylation PhosphoSitePlus
Y1613 Phosphorylation PhosphoSitePlus
S1616 Phosphorylation PhosphoSitePlus
Y1669 Phosphorylation PhosphoSitePlus
Y1679 Phosphorylation PhosphoSitePlus
S1884 Phosphorylation PhosphoSitePlus
Y1888 Phosphorylation PhosphoSitePlus
T1892 Phosphorylation PhosphoSitePlus
T1893 Phosphorylation PhosphoSitePlus
T1894 Phosphorylation PhosphoSitePlus
Y1927 Phosphorylation PhosphoSitePlus
Y1970 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T630 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S473 R473 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
S489 L489 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
S568 F568 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
S573 N573 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ] DOID:1909 / melanoma [ cosmic ]
S576 I576 Biomuta DOID:2394 / ovarian cancer [ tcga ] DOID:2994 / germ cell cancer [ cosmic ]
T1570 P1570 Biomuta DOID:5041 / esophageal cancer [ tcga ]
S1616 F1616 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
T1893 I1893 Biomuta DOID:1909 / melanoma [ tcga ]