iPTMnet Report for Q9NY35 (CLDND1)
Protein Information
| UniProt AC / UniProt ID | Q9NY35 / CLDN1_HUMAN |
| Protein Name | Claudin domain-containing protein 1 |
| Gene Name | Name: CLDND1 Synonyms:C3orf4;ORFNames:HSPC174,PSEC0054,UNQ2511/PRO6000; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9NY35 |
| PRO Name | claudin domain-containing protein 1 (human) |
| Definition | A claudin domain-containing protein 1 that is encoded in the genome of human. |
| Short Label | hCLDND1 |
| Category | organism-gene |
Q9NY35 (CLDND1) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| N42 | N-Glycosylation | score1 | GlyGen | 29741879, 24190977 | ||
| K48 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S56 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K62 | Ubiquitination | score1 | PhosphoSitePlus | |||
| N72 | N-Glycosylation | score2 | GlyGen UniProt | 29741879, 19349973, 24190977 | ||
| C106 | Methylation | score1 | IEDB | 31844290 | ||
| C139 | Methylation | score1 | IEDB | 31844290 | ||
| T245 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K248 | Ubiquitination | score1 | PhosphoSitePlus |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S4 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S4 | L4 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
| N42 | S42 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| S56 | R56 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S56 | C56 | Biomuta | DOID:10283 / prostate cancer [ cosmic ] | |
| K62 | N62 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic ] | |
| K248 | N248 | Biomuta | DOID:1319 / brain cancer [ cosmic ] |
DAG View