Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9NY35 / CLDN1_HUMAN
Protein Name Claudin domain-containing protein 1
Gene Name Name: CLDND1
Synonyms:C3orf4;ORFNames:HSPC174,PSEC0054,UNQ2511/PRO6000;
Organism Homo sapiens (Human)

PRO ID PR:Q9NY35
DAG View
PRO Name claudin domain-containing protein 1 (human)
Definition A claudin domain-containing protein 1 that is encoded in the genome of human.
Short Label hCLDND1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9NY35 (CLDND1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
N42 N-Glycosylation GlyGen 29741879, 24190977
K48 Ubiquitination PhosphoSitePlus
S56 Phosphorylation PhosphoSitePlus
K62 Ubiquitination PhosphoSitePlus
N72 N-Glycosylation GlyGen   UniProt 29741879, 19349973, 24190977
C106 Methylation IEDB 31844290
C139 Methylation IEDB 31844290
T245 Phosphorylation PhosphoSitePlus
K248 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S4 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S4 L4 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
N42 S42 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S56 R56 Biomuta DOID:4159 / skin cancer [ cosmic ]
S56 C56 Biomuta DOID:10283 / prostate cancer [ cosmic ]
K62 N62 Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
K248 N248 Biomuta DOID:1319 / brain cancer [ cosmic ]