iPTMnet Report for Q9NY33 (DPP3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9NY33 / DPP3_HUMAN
Protein Name Dipeptidyl peptidase 3
Gene Name Name: DPP3
Organism Homo sapiens (Human)

PRO ID PR:Q9NY33
DAG View
PRO Name dipeptidyl peptidase 3 isoforms 1/2/4 (human)
Definition A dipeptidyl peptidase 3 (human), isoforms 1, 2, and 4.
Short Label hDPP3/iso:[1/2/4]
Category organism-seqgroup

Interactive Sequence View

Select/align proteoforms across species


Q9NY33 (DPP3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 22814378, 22223895
S27 Phosphorylation PhosphoSitePlus
T29 Phosphorylation PhosphoSitePlus
K113 Ubiquitination PhosphoSitePlus
S130 Phosphorylation PhosphoSitePlus
S153 O-Glycosylation GlyGen 30379171, 28510447, 34725712, ...34229054
K165 Ubiquitination PhosphoSitePlus
K202 Ubiquitination PhosphoSitePlus
K209 Ubiquitination PhosphoSitePlus
S218 Phosphorylation PhosphoSitePlus
K233 Ubiquitination PhosphoSitePlus
K235 Ubiquitination PhosphoSitePlus
K257 Ubiquitination PhosphoSitePlus
K264 Ubiquitination PhosphoSitePlus
S272 Phosphorylation PhosphoSitePlus
T286 Phosphorylation PhosphoSitePlus
S289 Phosphorylation PhosphoSitePlus
K294 Acetylation PhosphoSitePlus
K294 Ubiquitination PhosphoSitePlus
S297 Phosphorylation PhosphoSitePlus
K337 Ubiquitination PhosphoSitePlus
K342 Ubiquitination PhosphoSitePlus
K405 Ubiquitination PhosphoSitePlus
S408 Phosphorylation PhosphoSitePlus
K423 Ubiquitination PhosphoSitePlus
T425 Phosphorylation phospho.ELM   PhosphoSitePlus 16097034
K459 Ubiquitination PhosphoSitePlus
K466 Ubiquitination PhosphoSitePlus
K498 Ubiquitination PhosphoSitePlus
K615 Ubiquitination PhosphoSitePlus
K629 Ubiquitination PhosphoSitePlus
S630 Phosphorylation PhosphoSitePlus
T631 Phosphorylation PhosphoSitePlus
Y641 Phosphorylation PhosphoSitePlus
K670 Ubiquitination PhosphoSitePlus
T677 Phosphorylation PhosphoSitePlus
S682 Phosphorylation PhosphoSitePlus
S692 Phosphorylation PhosphoSitePlus
R698 Methylation PhosphoSitePlus
S699 Phosphorylation PhosphoSitePlus
S701 Phosphorylation PhosphoSitePlus
K727 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S27 L27 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S130 R130 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S297 F297 Biomuta DOID:1612 / breast cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
K405 * Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T677 A677 Biomuta DOID:363 / uterine cancer [ icgc ]
R698 Q698 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ]