iPTMnet Report for Q9NXZ2 (DDX43)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9NXZ2 / DDX43_HUMAN
Protein Name Probable ATP-dependent RNA helicase DDX43
Gene Name Name: DDX43
Synonyms:HAGE;
Organism Homo sapiens (Human)

PRO ID PR:Q9NXZ2
DAG View
PRO Name probable ATP-dependent RNA helicase DDX43 (human)
Definition A probable ATP-dependent RNA helicase DDX43 that is encoded in the genome of human.
Short Label hDDX43
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9NXZ2 (DDX43) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
R47 Methylation PhosphoSitePlus
R85 Methylation PhosphoSitePlus
K89 Ubiquitination PhosphoSitePlus
S95 Phosphorylation PhosphoSitePlus
S110 Phosphorylation PhosphoSitePlus
S202 Phosphorylation PhosphoSitePlus
T203 Phosphorylation PhosphoSitePlus
T323 Phosphorylation PhosphoSitePlus
Y339 Phosphorylation PhosphoSitePlus
S346 Phosphorylation PhosphoSitePlus
T372 Phosphorylation PhosphoSitePlus
T544 Phosphorylation PhosphoSitePlus
T592 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R85 H85 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:2394 / ovarian cancer [ cosmic, icgc ]
R85 C85 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic, icgc ]
S110 L110 Biomuta [ cosmic ]