iPTMnet Report for Q9NXX6 (NSMCE4A)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9NXX6 / NSE4A_HUMAN
Protein Name Non-structural maintenance of chromosomes element 4 homolog A
Gene Name Name: NSMCE4A
Synonyms:C10orf86;ORFNames:PP4762;
Organism Homo sapiens (Human)

PRO ID PR:Q9NXX6
DAG View
PRO Name non-structural maintenance of chromosomes element 4 homolog A (human)
Definition A non-structural maintenance of chromosomes element 4 homolog A that is encoded in the genome of human.
Short Label hNSMCE4A
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9NXX6 (NSMCE4A) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S28 Phosphorylation PhosphoSitePlus
S30 Phosphorylation PhosphoSitePlus
S32 Phosphorylation PhosphoSitePlus
S35 Phosphorylation PhosphoSitePlus
S38 O-Glycosylation GlyGen 30379171
S38 Phosphorylation PhosphoSitePlus
T58 Phosphorylation phospho.ELM   PhosphoSitePlus 22067460
S61 Phosphorylation phospho.ELM   PhosphoSitePlus 22067460
S63 Phosphorylation phospho.ELM   PhosphoSitePlus 22067460
S72 Phosphorylation PhosphoSitePlus
C82 Methylation IEDB 31844290
K238 Ubiquitination PhosphoSitePlus
S258 Phosphorylation PhosphoSitePlus
T263 Phosphorylation PhosphoSitePlus
K265 Ubiquitination PhosphoSitePlus
T345 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 22067460, 17525332
K365 Ubiquitination PhosphoSitePlus
T375 Phosphorylation phospho.ELM   PhosphoSitePlus 22067460
S377 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 22067460, 17525332
K382 Ubiquitination PhosphoSitePlus
S384 Phosphorylation phospho.ELM   PhosphoSitePlus 22067460


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S35 W35 Biomuta DOID:4159 / skin cancer [ cosmic ]
S72 R72 Biomuta DOID:3571 / liver cancer [ cosmic ]
S258 F258 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S258 Y258 Biomuta DOID:3571 / liver cancer [ cosmic ]
T345 K345 Biomuta DOID:3571 / liver cancer [ cosmic ]