iPTMnet Report for Q9NXW9 (ALKBH4)
Protein Information
| UniProt AC / UniProt ID | Q9NXW9 / ALKB4_HUMAN |
| Protein Name | Alpha-ketoglutarate-dependent dioxygenase alkB homolog 4 |
| Gene Name | Name: ALKBH4 Synonyms:ABH4; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9NXW9 |
| PRO Name | alpha-ketoglutarate-dependent dioxygenase alkB homolog 4 (human) |
| Definition | An alpha-ketoglutarate-dependent dioxygenase alkB homolog 4 that is encoded in the genome of human. |
| Short Label | hALKBH4 |
| Category | organism-gene |
DAG ViewQ9NXW9 (ALKBH4) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| A2 | Acetylation | score1 | UniProt | 22814378, 22223895 | ||
| T8 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| K98 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y109 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K112 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K121 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y158 | Phosphorylation | score1 | PhosphoSitePlus | |||
| R249 | Methylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K112 | * | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| R249 | W249 | Biomuta | DOID:363 / uterine cancer [ icgc ] |
