iPTMnet Report for Q9NXW2 (DNAJB12)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9NXW2 / DJB12_HUMAN
Protein Name DnaJ homolog subfamily B member 12
Gene Name Name: DNAJB12
Organism Homo sapiens (Human)

PRO ID PR:Q9NXW2
DAG View
PRO Name DnaJ homolog subfamily B member 12 (human)
Definition A DnaJ homolog subfamily B member 12 that is encoded in the genome of human.
Short Label hDNAJB12
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9NXW2 (DNAJB12) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 22814378
K33 Ubiquitination PhosphoSitePlus
K53 Ubiquitination PhosphoSitePlus
K73 Ubiquitination PhosphoSitePlus
S81 Phosphorylation PhosphoSitePlus
K92 Ubiquitination PhosphoSitePlus
K103 Ubiquitination PhosphoSitePlus
K109 Ubiquitination PhosphoSitePlus
Y112 Phosphorylation PhosphoSitePlus
K136 Ubiquitination PhosphoSitePlus
K141 Ubiquitination PhosphoSitePlus
T156 Phosphorylation PhosphoSitePlus
Y158 Phosphorylation PhosphoSitePlus
S162 Phosphorylation PhosphoSitePlus
K166 Ubiquitination PhosphoSitePlus
K168 Ubiquitination PhosphoSitePlus
K177 Ubiquitination PhosphoSitePlus
S178 Phosphorylation PhosphoSitePlus
S214 Phosphorylation PhosphoSitePlus
Y321 Phosphorylation PhosphoSitePlus
Y341 Phosphorylation PhosphoSitePlus
Y345 Phosphorylation PhosphoSitePlus
Y352 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S81 L81 Biomuta DOID:1612 / breast cancer [ cosmic ]
S81 W81 Biomuta DOID:4159 / skin cancer [ cosmic ]
K136 N136 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
K168 N168 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
K177 R177 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S214 P214 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
Y345 C345 Biomuta DOID:10534 / stomach cancer [ cosmic ]