iPTMnet Report for Q9NXV2 (KCTD5)
Protein Information
UniProt AC / UniProt ID | Q9NXV2 / KCTD5_HUMAN |
Protein Name | BTB/POZ domain-containing protein KCTD5 |
Gene Name | Name: KCTD5 |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9NXV2 |
PRO Name | BTB/POZ domain-containing protein KCTD5 (human) |
Definition | A BTB/POZ domain-containing protein KCTD5 that is encoded in the genome of human. |
Short Label | hKCTD5 |
Category | organism-gene |
Q9NXV2 (KCTD5) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
A2 | Acetylation | score1 | UniProt | 20068231 | ||
S10 | Phosphorylation | score2 | HPRD PhosphoSitePlus UniProt | 23186163, 20068231 | ||
R13 | Methylation | score1 | PhosphoSitePlus | |||
R26 | Methylation | score1 | PhosphoSitePlus | |||
S29 | Phosphorylation | score1 | PhosphoSitePlus | |||
S41 | Phosphorylation | score1 | PhosphoSitePlus | |||
K67 | Ubiquitination | score1 | PhosphoSitePlus | |||
K115 | Ubiquitination | score1 | PhosphoSitePlus | |||
S147 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 18491316 | ||
K148 | Ubiquitination | score1 | PhosphoSitePlus | |||
K155 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y191 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y193 | Phosphorylation | score1 | PhosphoSitePlus | |||
K223 | Ubiquitination | score1 | PhosphoSitePlus | |||
K225 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
A2 | V2 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
A2 | S2 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
R13 | P13 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
S147 | N147 | Biomuta | DOID:363 / uterine cancer [ icgc ] DOID:1319 / brain cancer [ cosmic, icgc ] | |
K155 | T155 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
Y191 | C191 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] |