iPTMnet Report Q9NXV2 KCTD5

Protein Information

Cytoscape View

UniProt AC / UniProt ID	Q9NXV2 / KCTD5_HUMAN
Protein Name	BTB/POZ domain-containing protein KCTD5
Gene Name	Name: KCTD5
Organism	Homo sapiens (Human)

PRO ID	PR:Q9NXV2 DAG View
PRO Name	BTB/POZ domain-containing protein KCTD5 (human)
Definition	A BTB/POZ domain-containing protein KCTD5 that is encoded in the genome of human.
Short Label	hKCTD5
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

Q9NXV2 (KCTD5) as Substrate

Q9NXV2

Expanded View

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	A2	Acetylation		score1	UniProt	20068231
	S10	Phosphorylation		score2	HPRD PhosphoSitePlus UniProt	23186163, 20068231
	R13	Methylation		score1	PhosphoSitePlus
	R26	Methylation		score1	PhosphoSitePlus
	S29	Phosphorylation		score1	PhosphoSitePlus
	S41	Phosphorylation		score1	PhosphoSitePlus
	K67	Ubiquitination		score1	PhosphoSitePlus
	K115	Ubiquitination		score1	PhosphoSitePlus
	S147	Phosphorylation		score2	HPRD PhosphoSitePlus	18491316
	K148	Ubiquitination		score1	PhosphoSitePlus
	K155	Ubiquitination		score1	PhosphoSitePlus
	Y191	Phosphorylation		score1	PhosphoSitePlus
	Y193	Phosphorylation		score1	PhosphoSitePlus
	K223	Ubiquitination		score1	PhosphoSitePlus
	K225	Ubiquitination		score1	PhosphoSitePlus

PTM sites affected in variants

Site	Variant	Source	PMID	Disease [Sample source]
A2	V2	Biomuta		DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
A2	S2	Biomuta		DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
R13	P13	Biomuta		DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
S147	N147	Biomuta		DOID:363 / uterine cancer [ icgc ] DOID:1319 / brain cancer [ cosmic, icgc ]
K155	T155	Biomuta		DOID:363 / uterine cancer [ icgc ]
Y191	C191	Biomuta		DOID:363 / uterine cancer [ cosmic, icgc ]