Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9NXV2 / KCTD5_HUMAN
Protein Name BTB/POZ domain-containing protein KCTD5
Gene Name Name: KCTD5
Organism Homo sapiens (Human)

PRO ID PR:Q9NXV2
DAG View
PRO Name BTB/POZ domain-containing protein KCTD5 (human)
Definition A BTB/POZ domain-containing protein KCTD5 that is encoded in the genome of human.
Short Label hKCTD5
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9NXV2 (KCTD5) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 20068231
S10 Phosphorylation HPRD   PhosphoSitePlus   UniProt 23186163, 20068231
R13 Methylation PhosphoSitePlus
R26 Methylation PhosphoSitePlus
S29 Phosphorylation PhosphoSitePlus
S41 Phosphorylation PhosphoSitePlus
K67 Ubiquitination PhosphoSitePlus
K115 Ubiquitination PhosphoSitePlus
S147 Phosphorylation HPRD   PhosphoSitePlus 18491316
K148 Ubiquitination PhosphoSitePlus
K155 Ubiquitination PhosphoSitePlus
Y191 Phosphorylation PhosphoSitePlus
Y193 Phosphorylation PhosphoSitePlus
K223 Ubiquitination PhosphoSitePlus
K225 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
A2 V2 Biomuta DOID:3963 / thyroid carcinoma [ cosmic, icgc ]
A2 S2 Biomuta DOID:3963 / thyroid carcinoma [ cosmic, icgc ]
R13 P13 Biomuta DOID:3963 / thyroid carcinoma [ cosmic, icgc ]
S147 N147 Biomuta DOID:363 / uterine cancer [ tcga ] DOID:3070 / malignant glioma [ tcga ]
K155 T155 Biomuta DOID:363 / uterine cancer [ tcga ]
Y191 C191 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]