iPTMnet Report for Q9NXR7 (BABAM2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9NXR7 / BABA2_HUMAN
Protein Name BRISC and BRCA1-A complex member 2
Gene Name Name: BABAM2
Synonyms:BRCC45,BRE;
Organism Homo sapiens (Human)

PRO ID PR:Q9NXR7
DAG View
PRO Name BRISC and BRCA1-A complex member 2 (human)
Definition A BRISC and BRCA1-A complex member 2 that is encoded in the genome of human.
Short Label hBABAM2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9NXR7 (BABAM2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 19413330, 22223895, 20068231
S2 Phosphorylation PhosphoSitePlus   UniProt 23186163, 20068231
S15 Phosphorylation PhosphoSitePlus
K26 Ubiquitination PhosphoSitePlus
K41 Ubiquitination PhosphoSitePlus
K57 Ubiquitination PhosphoSitePlus
K162 Ubiquitination PhosphoSitePlus
K176 Ubiquitination PhosphoSitePlus
Y263 Phosphorylation PhosphoSitePlus
K270 Acetylation PhosphoSitePlus
S350 Phosphorylation PhosphoSitePlus
K360 Ubiquitination PhosphoSitePlus
K367 Ubiquitination PhosphoSitePlus
K382 Acetylation PhosphoSitePlus
K382 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S2 Phosphorylation HPRD 18691976, 20068231
S350 Phosphorylation HPRD 20068231
K389 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S2 Phosphorylation HPRD 18691976, 20068231
S350 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
S374 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S2 Phosphorylation HPRD 18691976, 20068231
S350 Phosphorylation HPRD 20068231
S366 Phosphorylation PhosphoSitePlus
S373 Phosphorylation PhosphoSitePlus
S374 Phosphorylation PhosphoSitePlus
S375 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K176 N176 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y263 C263 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ] DOID:3571 / liver cancer [ cosmic ]
S350 N350 Biomuta DOID:3571 / liver cancer [ cosmic ]
S374 R374 Biomuta DOID:4362 / cervical cancer [ icgc ]
K382 R382 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ] DOID:3571 / liver cancer [ cosmic ]