iPTMnet Report for Q9NXL9 (MCM9)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9NXL9 / MCM9_HUMAN
Protein Name DNA helicase MCM9
Gene Name Name: MCM9
Synonyms:C6orf61,MCMDC1;
Organism Homo sapiens (Human)

PRO ID PR:Q9NXL9
DAG View
PRO Name DNA helicase MCM9 (human)
Definition A DNA helicase MCM9 that is encoded in the genome of human.
Short Label hMCM9
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9NXL9 (MCM9) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T79 Phosphorylation PhosphoSitePlus
S83 Phosphorylation PhosphoSitePlus
S85 Phosphorylation PhosphoSitePlus
S91 Phosphorylation PhosphoSitePlus
K93 Ubiquitination PhosphoSitePlus
K137 Ubiquitination PhosphoSitePlus
K249 Ubiquitination PhosphoSitePlus
K296 Ubiquitination PhosphoSitePlus
S309 Phosphorylation PhosphoSitePlus
Y318 Phosphorylation PhosphoSitePlus
K358 Ubiquitination PhosphoSitePlus
K367 Ubiquitination PhosphoSitePlus
K440 Ubiquitination PhosphoSitePlus
K446 Ubiquitination PhosphoSitePlus
S515 Phosphorylation PhosphoSitePlus
S663 Phosphorylation PhosphoSitePlus
S707 Phosphorylation PhosphoSitePlus
S741 Phosphorylation PhosphoSitePlus
S762 Phosphorylation PhosphoSitePlus   UniProt 23186163, 20068231
S802 Phosphorylation PhosphoSitePlus   UniProt 23186163
S878 Phosphorylation PhosphoSitePlus
S883 Phosphorylation PhosphoSitePlus
S890 Phosphorylation PhosphoSitePlus
S898 Phosphorylation PhosphoSitePlus
S915 Phosphorylation PhosphoSitePlus
S942 Phosphorylation PhosphoSitePlus
S952 Phosphorylation PhosphoSitePlus
T1064 Phosphorylation PhosphoSitePlus
S1069 Phosphorylation phospho.ELM 18669648
S1087 Phosphorylation PhosphoSitePlus
S1088 Phosphorylation PhosphoSitePlus
S1103 Phosphorylation PhosphoSitePlus
R1107 Methylation PhosphoSitePlus
S1109 Phosphorylation PhosphoSitePlus   UniProt 23186163
T1110 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K358 E358 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K367 T367 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K446 R446 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S952 I952 Biomuta DOID:363 / uterine cancer [ icgc ]
S1087 I1087 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S1087 G1087 Biomuta DOID:10534 / stomach cancer [ cosmic ]
R1107 C1107 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:9256 / colorectal cancer [ cosmic ]