iPTMnet Report for Q9NXJ5 (PGPEP1)
Protein Information
| UniProt AC / UniProt ID | Q9NXJ5 / PGPI_HUMAN |
| Protein Name | Pyroglutamyl-peptidase 1 |
| Gene Name | Name: PGPEP1 Synonyms:PGPI; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9NXJ5 |
| PRO Name | pyroglutamyl-peptidase 1 (human) |
| Definition | A pyroglutamyl-peptidase 1 that is encoded in the genome of human. |
| Short Label | hPGPEP1 |
| Category | organism-gene |
DAG ViewQ9NXJ5 (PGPEP1) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| Y45 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K94 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C126 | Methylation | score1 | IEDB | 31844290 | ||
| Y147 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y153 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y158 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S160 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K174 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| Y158 | D158 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
| K174 | R174 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |
