iPTMnet Report for Q9NXC5 (MIOS)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9NXC5 / MIOS_HUMAN
Protein Name GATOR2 complex protein MIOS
Gene Name Name: MIOS
Organism Homo sapiens (Human)

PRO ID PR:Q9NXC5
DAG View
PRO Name GATOR complex protein MIOS (human)
Definition A GATOR complex protein MIOS that is encoded in the genome of human.
Short Label hMIOS
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9NXC5 (MIOS) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Phosphorylation PhosphoSitePlus
K5 Acetylation PhosphoSitePlus
K106 Ubiquitination PhosphoSitePlus
C191 Methylation IEDB 31844290
T231 Phosphorylation PhosphoSitePlus
Y235 Phosphorylation PhosphoSitePlus
T280 Phosphorylation PhosphoSitePlus
T285 Phosphorylation PhosphoSitePlus
C321 S-Nitrosylation dbSNO 26338901
K393 Ubiquitination PhosphoSitePlus
Y436 Phosphorylation PhosphoSitePlus
K448 Ubiquitination PhosphoSitePlus
S450 Phosphorylation PhosphoSitePlus
Y453 Phosphorylation PhosphoSitePlus
K479 Ubiquitination PhosphoSitePlus
S481 Phosphorylation PhosphoSitePlus
S570 Phosphorylation PhosphoSitePlus
S577 Phosphorylation PhosphoSitePlus
T578 Phosphorylation PhosphoSitePlus
S664 Phosphorylation PhosphoSitePlus
Y665 Phosphorylation PhosphoSitePlus
C740 Methylation IEDB 31844290
R756 Methylation PhosphoSitePlus
S759 Phosphorylation PhosphoSitePlus   UniProt 23186163
Y761 Phosphorylation PhosphoSitePlus
S764 Phosphorylation PhosphoSitePlus
S766 Phosphorylation PhosphoSitePlus   UniProt 21406692, 23186163, 18669648, ...19690332, 20068231
T768 Phosphorylation PhosphoSitePlus
S770 Phosphorylation PhosphoSitePlus
T773 Phosphorylation PhosphoSitePlus
S774 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S766 Phosphorylation HPRD 19413330, 18691976, 20058876, ...19664994, 19664995, 18669648, 19415658, 20068231
T768 Phosphorylation HPRD 19664995, 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
C321 G321 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K479 N479 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S481 N481 Biomuta DOID:3571 / liver cancer [ cosmic ]
R756 T756 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S766 T766 Biomuta DOID:10283 / prostate cancer [ cosmic, icgc ]
S770 Y770 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
T773 I773 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]