Protein Information

Cytoscape View

UniProt AC / UniProt ID Q9NX63 / MIC19_HUMAN
Protein Name MICOS complex subunit MIC19
Gene Name Name: CHCHD3
Organism Homo sapiens (Human)

DAG View
PRO Name MICOS complex subunit MIC19 (human)
Definition A MICOS complex subunit MIC19 that is encoded in the genome of human.
Short Label hCHCHD3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

Q9NX63 (CHCHD3) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
G2 Myristoylation UniProt 25255805
T11 Phosphorylation P17612 (PRKACA) neXtProt   PhosphoSitePlus   RLIMS-P 17242405, 21081504
S29 Phosphorylation PhosphoSitePlus   UniProt 23186163
R35 Methylation PhosphoSitePlus
S44 O-Glycosylation GlyGen 28411811, 28510447, 29351928
S46 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 20166139, 18669648
Y49 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18691976, 23186163, 19664994, ...18669648, 19690332
S50 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 18212344, ...18767875, 19664995, 19007248, 19651622, 18669648, 20166139, 16565220, 19690332, 20068231, 19691289
Y53 Phosphorylation PhosphoSitePlus
S56 Phosphorylation HPRD   PhosphoSitePlus 19691289
S58 Phosphorylation PhosphoSitePlus   UniProt 23186163
K63 Acetylation PhosphoSitePlus
K63 Ubiquitination PhosphoSitePlus
K76 Ubiquitination PhosphoSitePlus
K77 Ubiquitination PhosphoSitePlus
S79 Phosphorylation PhosphoSitePlus
S113 Phosphorylation PhosphoSitePlus
K136 Ubiquitination PhosphoSitePlus
Y141 Phosphorylation PhosphoSitePlus
K142 Acetylation PhosphoSitePlus   UniProt 19608861
K142 Ubiquitination PhosphoSitePlus
K165 Ubiquitination PhosphoSitePlus
K173 Acetylation PhosphoSitePlus
K173 Ubiquitination PhosphoSitePlus
Y177 Phosphorylation PhosphoSitePlus
S179 Phosphorylation PhosphoSitePlus
K189 Ubiquitination PhosphoSitePlus
T198 Phosphorylation PhosphoSitePlus
K225 Ubiquitination PhosphoSitePlus

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S29 L29 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc, tcga ]
S50 F50 Biomuta DOID:263 / kidney cancer [ cosmic, icgc, tcga ]
S56 * Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc, tcga ]
S58 F58 Biomuta DOID:1324 / lung cancer [ cosmic ]
Y141 * Biomuta DOID:3571 / liver cancer [ icgc ]
K173 T173 Biomuta DOID:263 / kidney cancer [ cosmic, icgc, tcga ]