Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9NX47 / MARH5_HUMAN
Protein Name E3 ubiquitin-protein ligase MARCHF5
Gene Name Name: MARCHF5
Synonyms:MARCH5,RNF153;
Organism Homo sapiens (Human)

PRO ID PR:Q9NX47
DAG View
PRO Name E3 ubiquitin-protein ligase MARCHF5 (human)
Definition An E3 ubiquitin-protein ligase MARCHF5 that is encoded in the genome of human.
Short Label hMARCHF5
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9NX47 (MARCHF5) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K40 Ubiquitination PhosphoSitePlus
C46 S-Nitrosylation dbSNO 21278135
K54 Ubiquitination PhosphoSitePlus
Y164 Phosphorylation PhosphoSitePlus
T238 O-Glycosylation GlyGen 30379171
K257 Ubiquitination PhosphoSitePlus
K268 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
C46 Y46 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]