iPTMnet Report for Q9NWT6 (HIF1AN)
Protein Information
| UniProt AC / UniProt ID | Q9NWT6 / HIF1N_HUMAN |
| Protein Name | Hypoxia-inducible factor 1-alpha inhibitor |
| Gene Name | Name: HIF1AN Synonyms:FIH1; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9NWT6 |
| PRO Name | hypoxia-inducible factor 1-alpha inhibitor (human) |
| Definition | A hypoxia-inducible factor 1-alpha inhibitor that is encoded in the genome of human. |
| Short Label | hHIF1AN |
| Category | organism-gene |
DAG ViewQ9NWT6 (HIF1AN) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| A2 | Acetylation | score1 | UniProt | 19413330, 22814378, 22223895 | ||
| K75 | Sumoylation | score1 | PhosphoSitePlus | |||
| Y102 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K115 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K131 | Ubiquitination | score1 | PhosphoSitePlus | |||
| R138 | Methylation | score1 | PhosphoSitePlus | |||
| C226 | Methylation | score1 | IEDB | 31844290 | ||
| K311 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K315 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K345 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K311 | N311 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
| K345 | R345 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
| K345 | N345 | Biomuta | DOID:1324 / lung cancer [ cosmic ] |
