Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9NWT6 / HIF1N_HUMAN
Protein Name Hypoxia-inducible factor 1-alpha inhibitor
Gene Name Name: HIF1AN
Synonyms:FIH1;
Organism Homo sapiens (Human)

PRO ID PR:Q9NWT6
DAG View
PRO Name hypoxia-inducible factor 1-alpha inhibitor (human)
Definition A hypoxia-inducible factor 1-alpha inhibitor that is encoded in the genome of human.
Short Label hHIF1AN
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9NWT6 (HIF1AN) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330, 22814378, 22223895
Y102 Phosphorylation PhosphoSitePlus
K115 Ubiquitination PhosphoSitePlus
K131 Ubiquitination PhosphoSitePlus
R138 Methylation PhosphoSitePlus
K311 Ubiquitination PhosphoSitePlus
K315 Ubiquitination PhosphoSitePlus
K345 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K311 N311 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
K345 N345 Biomuta DOID:1324 / lung cancer [ cosmic ]