iPTMnet Report for Q9NWT1 (PAK1IP1)
Protein Information
UniProt AC / UniProt ID | Q9NWT1 / PK1IP_HUMAN |
Protein Name | p21-activated protein kinase-interacting protein 1 |
Gene Name | Name: PAK1IP1 Synonyms:PIP1,WDR84; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9NWT1 |
PRO Name | p21-activated protein kinase-interacting protein 1 (human) |
Definition | A p21-activated protein kinase-interacting protein 1 that is encoded in the genome of human. |
Short Label | hPAK1IP1 |
Category | organism-gene |
Q9NWT1 (PAK1IP1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K70 | Acetylation | score1 | PhosphoSitePlus | |||
K111 | Acetylation | score1 | PhosphoSitePlus | |||
S118 | Phosphorylation | score1 | PhosphoSitePlus | |||
T127 | Phosphorylation | score1 | PhosphoSitePlus | |||
S130 | Phosphorylation | score1 | PhosphoSitePlus | |||
K145 | Ubiquitination | score1 | PhosphoSitePlus | |||
K161 | Ubiquitination | score1 | PhosphoSitePlus | |||
S173 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y179 | Phosphorylation | score1 | PhosphoSitePlus | |||
S214 | Phosphorylation | score1 | PhosphoSitePlus | |||
S320 | Phosphorylation | score2 | HPRD phospho.ELM PhosphoSitePlus UniProt | 19413330, 21406692, 23186163, ... | ||
S323 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 17322306, 19413330 | ||
T337 | Phosphorylation | score1 | PhosphoSitePlus | |||
K363 | Ubiquitination | score1 | PhosphoSitePlus | |||
S365 | Phosphorylation | score0 | HPRD | 19691289 | ||
S369 | Phosphorylation | score1 | PhosphoSitePlus | |||
K372 | Acetylation | score1 | PhosphoSitePlus | |||
K381 | Acetylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K111 | N111 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
S173 | P173 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
S320 | Y320 | Biomuta | DOID:363 / uterine cancer [ icgc ] |