iPTMnet Report for Q9NWS9 (ZNF446)
Protein Information
UniProt AC / UniProt ID | Q9NWS9 / ZN446_HUMAN |
Protein Name | Zinc finger protein 446 |
Gene Name | Name: ZNF446 Synonyms:ZKSCAN20; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9NWS9 |
PRO Name | zinc finger protein 446 (human) |
Definition | A zinc finger protein 446 that is encoded in the genome of human. |
Short Label | hZNF446 |
Category | organism-gene |
Q9NWS9 (ZNF446) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S3 | Phosphorylation | score1 | PhosphoSitePlus | |||
T131 | Phosphorylation | score1 | PhosphoSitePlus | |||
S137 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 21406692, 23186163, 19690332, ... | ||
S141 | Phosphorylation | score1 | PhosphoSitePlus | |||
S146 | Phosphorylation | score1 | PhosphoSitePlus | |||
S159 | Phosphorylation | score1 | PhosphoSitePlus | |||
S188 | Phosphorylation | score1 | PhosphoSitePlus | |||
S218 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
K220 | Ubiquitination | score1 | PhosphoSitePlus | |||
T303 | Phosphorylation | score1 | PhosphoSitePlus | |||
T308 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
T320 | Phosphorylation | score1 | PhosphoSitePlus | |||
T327 | Phosphorylation | score1 | PhosphoSitePlus | |||
K330 | Sumoylation | score1 | PhosphoSitePlus | |||
S362 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S3 | F3 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
T131 | R131 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
T131 | A131 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
T131 | I131 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
S159 | Y159 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
S188 | F188 | Biomuta | DOID:1612 / breast cancer [ icgc ] | |
T320 | M320 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
T327 | P327 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] |