Protein Information

Cytoscape View

UniProt AC / UniProt ID Q9NWA0 / MED9_HUMAN
Protein Name Mediator of RNA polymerase II transcription subunit 9
Gene Name Name: MED9
Organism Homo sapiens (Human)

DAG View
PRO Name mediator of RNA polymerase II transcription subunit 9 (human)
Definition A mediator of RNA polymerase II transcription subunit 9 that is encoded in the genome of human.
Short Label hMED9
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

Q9NWA0 (MED9) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 22814378
S3 Phosphorylation PhosphoSitePlus
T19 Phosphorylation HPRD 18691976
S20 Phosphorylation HPRD 18691976
S46 Phosphorylation HPRD   PhosphoSitePlus 20068231
S53 Phosphorylation HPRD   PhosphoSitePlus 20068231
Y63 Phosphorylation PhosphoSitePlus
S64 Phosphorylation PhosphoSitePlus
S80 Phosphorylation PhosphoSitePlus
K91 Ubiquitination PhosphoSitePlus
K99 Ubiquitination PhosphoSitePlus
S110 Phosphorylation HPRD   PhosphoSitePlus   UniProt 23186163, 20068231
K128 Sumoylation PhosphoSitePlus
K134 Ubiquitination PhosphoSitePlus
K136 Ubiquitination PhosphoSitePlus
K145 Ubiquitination PhosphoSitePlus

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T19 K19 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
K136 * Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc, tcga ]