iPTMnet Report for Q9NW64 (RBM22)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9NW64 / RBM22_HUMAN
Protein Name Pre-mRNA-splicing factor RBM22
Gene Name Name: RBM22
Synonyms:ZC3H16;ORFNames:199G4;
Organism Homo sapiens (Human)

PRO ID PR:Q9NW64
DAG View
PRO Name pre-mRNA-splicing factor RBM22 (human)
Definition A pre-mRNA-splicing factor RBM22 that is encoded in the genome of human.
Short Label hRBM22
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9NW64 (RBM22) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330, 22814378, 22223895
S4 Phosphorylation PhosphoSitePlus   UniProt 23186163
Y33 Phosphorylation PhosphoSitePlus
K76 Ubiquitination PhosphoSitePlus
K78 Ubiquitination PhosphoSitePlus
Y90 Phosphorylation PhosphoSitePlus
S102 Phosphorylation PhosphoSitePlus   UniProt 23186163
K104 Ubiquitination PhosphoSitePlus
K109 Sumoylation PhosphoSitePlus
K114 Ubiquitination PhosphoSitePlus
Y116 Phosphorylation PhosphoSitePlus
Y117 Phosphorylation PhosphoSitePlus
T118 Phosphorylation PhosphoSitePlus
S126 O-Glycosylation GlyGen 30379171, 34019948, 28510447
S126 Phosphorylation PhosphoSitePlus
K139 Methylation PhosphoSitePlus
K139 Ubiquitination PhosphoSitePlus
T141 O-Glycosylation GlyGen 31373491
S142 Phosphorylation PhosphoSitePlus
K149 Methylation PhosphoSitePlus
K149 Sumoylation PhosphoSitePlus
K149 Ubiquitination PhosphoSitePlus
Y156 Phosphorylation PhosphoSitePlus
Y157 Phosphorylation PhosphoSitePlus
K170 Ubiquitination PhosphoSitePlus
K185 Methylation PhosphoSitePlus
K199 Ubiquitination PhosphoSitePlus
Y202 Phosphorylation PhosphoSitePlus
K212 Acetylation PhosphoSitePlus   UniProt 19608861
K212 Ubiquitination PhosphoSitePlus
T219 Phosphorylation PhosphoSitePlus
C269 Methylation IEDB 31844290
K290 Sumoylation PhosphoSitePlus
K324 Sumoylation PhosphoSitePlus
R395 Methylation PhosphoSitePlus
S404 Phosphorylation PhosphoSitePlus
K416 Acetylation PhosphoSitePlus
S419 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T3 Phosphorylation HPRD 20068231
S4 Phosphorylation HPRD 20068231
S126 Phosphorylation HPRD 20068231
T131 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T3 A3 Biomuta DOID:4159 / skin cancer [ cosmic ]
S4 Y4 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T131 A131 Biomuta DOID:9256 / colorectal cancer [ icgc ]
K199 N199 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
R395 W395 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:3565 / meningioma [ cosmic ] DOID:1324 / lung cancer [ cosmic ]
R395 Q395 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
S419 R419 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]