iPTMnet Report for Q9NW08 (POLR3B)
Protein Information
| UniProt AC / UniProt ID | Q9NW08 / RPC2_HUMAN |
| Protein Name | DNA-directed RNA polymerase III subunit RPC2 |
| Gene Name | Name: POLR3B |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9NW08 |
| PRO Name | DNA-directed RNA polymerase III subunit RPC2 (human) |
| Definition | A DNA-directed RNA polymerase III subunit RPC2 that is encoded in the genome of human. |
| Short Label | hPOLR3B |
| Category | organism-gene |
DAG ViewQ9NW08 (POLR3B) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| T12 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K64 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K157 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K172 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K186 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K196 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S202 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 17287340 | ||
| S206 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 17287340 | ||
| K210 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K290 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T304 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K324 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K394 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K404 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S457 | O-Glycosylation | score1 | GlyGen | 30379171 | ||
| K601 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K609 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S680 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K691 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T707 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y710 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y714 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T722 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K723 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S816 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K820 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K824 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K830 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K852 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K859 | Methylation | score1 | PhosphoSitePlus | |||
| K859 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S872 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S873 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K896 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K950 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K968 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K970 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K1013 | Methylation | score1 | PhosphoSitePlus | |||
| K1019 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T1036 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K186 | N186 | Biomuta | DOID:1319 / brain cancer [ cosmic, icgc ] | |
| S202 | L202 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| S206 | C206 | Biomuta | DOID:4362 / cervical cancer [ cosmic, icgc ] | |
| S206 | P206 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| K394 | * | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| S457 | F457 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S816 | F816 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| K968 | T968 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| T1036 | I1036 | Biomuta | DOID:4159 / skin cancer [ cosmic ] |
