iPTMnet Report for Q9NVX7 (KBTBD4)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9NVX7 / KBTB4_HUMAN
Protein Name Kelch repeat and BTB domain-containing protein 4
Gene Name Name: KBTBD4
Synonyms:BKLHD4;
Organism Homo sapiens (Human)

PRO ID PR:Q9NVX7
DAG View
PRO Name kelch repeat and BTB domain-containing protein 4 (human)
Definition A kelch repeat and BTB domain-containing protein 4 that is encoded in the genome of human.
Short Label hKBTBD4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9NVX7 (KBTBD4) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S3 Phosphorylation PhosphoSitePlus
S10 Phosphorylation PhosphoSitePlus
K167 Ubiquitination PhosphoSitePlus
K171 Ubiquitination PhosphoSitePlus
K232 Ubiquitination PhosphoSitePlus
Y241 Phosphorylation PhosphoSitePlus
K245 Ubiquitination PhosphoSitePlus
C274 Methylation IEDB 31844290
K300 Ubiquitination PhosphoSitePlus
K329 Ubiquitination PhosphoSitePlus
K338 Ubiquitination PhosphoSitePlus
Y350 Phosphorylation PhosphoSitePlus
Y351 Phosphorylation PhosphoSitePlus
K413 Ubiquitination PhosphoSitePlus
Y415 Phosphorylation PhosphoSitePlus
C443 Methylation IEDB 31844290
K492 Ubiquitination PhosphoSitePlus
T501 Phosphorylation PhosphoSitePlus
T503 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
K2 Methylation PhosphoSitePlus
Y31 Phosphorylation PhosphoSitePlus
Y35 Phosphorylation PhosphoSitePlus
T36 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K338 T338 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y350 * Biomuta DOID:3571 / liver cancer [ cosmic ]
Y415 C415 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
C443 Y443 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]