iPTMnet Report for Q9NVV0 (TMEM38B)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9NVV0 / TM38B_HUMAN
Protein Name Trimeric intracellular cation channel type B
Gene Name Name: TMEM38B
Synonyms:C9orf87;
Organism Homo sapiens (Human)

PRO ID PR:Q9NVV0
DAG View
PRO Name trimeric intracellular cation channel type B (human)
Definition A trimeric intracellular cation channel type B that is encoded in the genome of human.
Short Label hTMEM38B
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9NVV0 (TMEM38B) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K166 Ubiquitination PhosphoSitePlus
K170 Ubiquitination PhosphoSitePlus
T186 Phosphorylation PhosphoSitePlus
S190 Phosphorylation PhosphoSitePlus
S258 Phosphorylation PhosphoSitePlus
S262 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18691976, 18669648, 20068231
S264 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18691976, 18669648
S269 Phosphorylation HPRD   phospho.ELM 18669648
K273 Ubiquitination PhosphoSitePlus
S279 Phosphorylation HPRD   PhosphoSitePlus 19007248


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T186 I186 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S190 T190 Biomuta DOID:3571 / liver cancer [ cosmic ]
S258 R258 Biomuta DOID:363 / uterine cancer [ icgc ]
S258 I258 Biomuta DOID:1319 / brain cancer [ icgc ]
S269 L269 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S279 L279 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S279 T279 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]