iPTMnet Report for Q9NVU7 (SDAD1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9NVU7 / SDA1_HUMAN
Protein Name Protein SDA1 homolog
Gene Name Name: SDAD1
Synonyms:NUC130;
Organism Homo sapiens (Human)

PRO ID PR:Q9NVU7
DAG View
PRO Name protein SDA1 homolog (human)
Definition A protein SDA1 that is encoded in the genome of human.
Short Label hSDAD1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9NVU7 (SDAD1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S11 Phosphorylation PhosphoSitePlus
K21 Ubiquitination PhosphoSitePlus
C69 Methylation IEDB 31844290
Y138 Phosphorylation PhosphoSitePlus
S172 Phosphorylation PhosphoSitePlus
T175 Phosphorylation PhosphoSitePlus
S208 Phosphorylation PhosphoSitePlus
S232 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S234 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S236 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
K254 Acetylation PhosphoSitePlus
R310 Methylation PhosphoSitePlus
S322 Phosphorylation PhosphoSitePlus
R341 Methylation PhosphoSitePlus
T434 Phosphorylation PhosphoSitePlus
T441 Phosphorylation PhosphoSitePlus
K454 Ubiquitination PhosphoSitePlus
S459 Phosphorylation PhosphoSitePlus
Y467 Phosphorylation PhosphoSitePlus
K473 Sumoylation PhosphoSitePlus
S501 Phosphorylation PhosphoSitePlus
S518 Phosphorylation PhosphoSitePlus
S519 Phosphorylation PhosphoSitePlus
S532 Phosphorylation PhosphoSitePlus
K539 Methylation PhosphoSitePlus
K541 Methylation PhosphoSitePlus
T552 Phosphorylation PhosphoSitePlus   UniProt 23186163
K558 Ubiquitination PhosphoSitePlus
Y580 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S585 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18691976, 21406692, 23186163, ...17081983, 18220336, 18669648, 24275569, 20068231
S595 Phosphorylation PhosphoSitePlus   UniProt 21406692
T616 Phosphorylation PhosphoSitePlus
T634 Phosphorylation PhosphoSitePlus
K643 Acetylation PhosphoSitePlus
Y656 Phosphorylation PhosphoSitePlus
S657 Phosphorylation PhosphoSitePlus
S662 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S11 Phosphorylation HPRD 20068231
S232 Phosphorylation HPRD 19651622, 18669648
S234 Phosphorylation HPRD 19651622, 18669648
S236 Phosphorylation HPRD 19651622, 18669648
T441 Phosphorylation HPRD 20068231
T456 Phosphorylation HPRD 20068231
S459 Phosphorylation HPRD 19007248
Y467 Phosphorylation HPRD 20068231
Y580 Phosphorylation HPRD 18669648, 20068231
S585 Phosphorylation HPRD 19413330, 18691976, 17081983, ...20230923, 18767875, 20058876, 19007248, 19664995, 19651622, 19664994, 18669648, 19415658, 20068231, 19691289
Y656 Phosphorylation HPRD 18491316
S657 Phosphorylation HPRD 18491316
S662 Phosphorylation HPRD 18491316


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S11 I11 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T175 I175 Biomuta DOID:4159 / skin cancer [ cosmic ]
K254 E254 Biomuta DOID:3571 / liver cancer [ cosmic ]
R341 T341 Biomuta DOID:3571 / liver cancer [ cosmic ]
T434 I434 Biomuta [ cosmic ]
Y467 C467 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
K473 E473 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S518 P518 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
K643 T643 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S662 L662 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]