iPTMnet Report for Q9NVR2 (INTS10)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9NVR2 / INT10_HUMAN
Protein Name Integrator complex subunit 10
Gene Name Name: INTS10
Synonyms:C8orf35;
Organism Homo sapiens (Human)

PRO ID PR:Q9NVR2
DAG View
PRO Name integrator complex subunit 10 (human)
Definition An integrator complex subunit 10 that is encoded in the genome of human.
Short Label hINTS10
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9NVR2 (INTS10) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Phosphorylation PhosphoSitePlus
K26 Ubiquitination PhosphoSitePlus
S81 Phosphorylation PhosphoSitePlus
T84 O-Glycosylation GlyGen 30379171
T84 Phosphorylation PhosphoSitePlus
S85 O-Glycosylation GlyGen 30379171
K94 Ubiquitination PhosphoSitePlus
K172 Ubiquitination PhosphoSitePlus
S227 Phosphorylation PhosphoSitePlus
S231 Phosphorylation HPRD   PhosphoSitePlus   UniProt 18691976, 23186163, 18452278, ...20166139, 19690332, 17924679
S233 Phosphorylation PhosphoSitePlus
K234 Ubiquitination PhosphoSitePlus
K239 Ubiquitination PhosphoSitePlus
K248 Ubiquitination PhosphoSitePlus
K261 Ubiquitination PhosphoSitePlus
S280 Phosphorylation PhosphoSitePlus
Y281 Phosphorylation PhosphoSitePlus
S300 Phosphorylation PhosphoSitePlus
Y306 Phosphorylation PhosphoSitePlus
Y312 Phosphorylation PhosphoSitePlus
T314 Phosphorylation PhosphoSitePlus
T379 Phosphorylation PhosphoSitePlus
S381 Phosphorylation PhosphoSitePlus
S382 Phosphorylation PhosphoSitePlus
S388 Phosphorylation PhosphoSitePlus
K414 Ubiquitination PhosphoSitePlus
Y424 Phosphorylation PhosphoSitePlus
Y458 Phosphorylation PhosphoSitePlus
Y462 Phosphorylation PhosphoSitePlus
K464 Sumoylation PhosphoSitePlus
C502 Methylation IEDB 33981976, 31844290
C564 Methylation IEDB 31844290
T578 Phosphorylation PhosphoSitePlus
K672 Acetylation PhosphoSitePlus
K702 Ubiquitination PhosphoSitePlus
T708 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K172 Q172 Biomuta DOID:9256 / colorectal cancer [ icgc ]
S231 L231 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
K239 E239 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
K239 N239 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S280 C280 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S280 R280 Biomuta DOID:10534 / stomach cancer [ cosmic ]
Y312 F312 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K414 T414 Biomuta DOID:363 / uterine cancer [ icgc ]
Y462 N462 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
C564 Y564 Biomuta DOID:1319 / brain cancer [ cosmic ]