iPTMnet Report Q9NVH6 TMLHE

Protein Information

Cytoscape View

UniProt AC / UniProt ID	Q9NVH6 / TMLH_HUMAN
Protein Name	Trimethyllysine dioxygenase, mitochondrial precursor
Gene Name	Name: TMLHE Synonyms:TMLH;
Organism	Homo sapiens (Human)

PRO ID	PR:Q9NVH6 DAG View
PRO Name	trimethyllysine dioxygenase, mitochondrial (human)
Definition	A trimethyllysine dioxygenase, mitochondrial that is encoded in the genome of human.
Short Label	hTMLHE
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

Q9NVH6 (TMLHE) as Substrate

Q9NVH6

Expanded View

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	K89	Acetylation		score1	PhosphoSitePlus
	T119	Phosphorylation		score1	PhosphoSitePlus
	T126	Phosphorylation		score1	PhosphoSitePlus
	K135	Ubiquitination		score1	PhosphoSitePlus
	K144	Ubiquitination		score1	PhosphoSitePlus
	K236	Acetylation		score2	PhosphoSitePlus UniProt	19608861
	K236	Ubiquitination		score1	PhosphoSitePlus
	K294	Ubiquitination		score1	PhosphoSitePlus

PTM sites affected in variants

Site	Variant	Source	PMID	Disease [Sample source]
K89	N89	Biomuta		DOID:4159 / skin cancer [ cosmic ]
K135	N135	Biomuta		DOID:9256 / colorectal cancer [ icgc ]