iPTMnet Report for Q9NVF7 (FBXO28)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9NVF7 / FBX28_HUMAN
Protein Name F-box only protein 28
Gene Name Name: FBXO28
Synonyms:CENP-30;
Organism Homo sapiens (Human)

PRO ID PR:Q9NVF7
DAG View
PRO Name F-box only protein 28 (human)
Definition An F-box only protein 28 that is encoded in the genome of human.
Short Label hFBXO28
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9NVF7 (FBXO28) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K108 Ubiquitination PhosphoSitePlus
K118 Ubiquitination PhosphoSitePlus
S129 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
Y178 Phosphorylation PhosphoSitePlus
Y210 Phosphorylation PhosphoSitePlus
K220 Ubiquitination PhosphoSitePlus
S226 Phosphorylation PhosphoSitePlus
S235 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S242 Phosphorylation PhosphoSitePlus   UniProt 20068231
K263 Ubiquitination PhosphoSitePlus
K269 Ubiquitination PhosphoSitePlus
T270 Phosphorylation PhosphoSitePlus   UniProt 20068231
T276 Phosphorylation PhosphoSitePlus
S283 Phosphorylation PhosphoSitePlus
K294 Ubiquitination PhosphoSitePlus
K302 Ubiquitination PhosphoSitePlus
S330 Phosphorylation PhosphoSitePlus
S344 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 21406692, 23186163, 17081983, ...23776131, 18669648, 19690332, 20068231
K347 Ubiquitination PhosphoSitePlus
S357 Phosphorylation PhosphoSitePlus
S361 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S235 Phosphorylation HPRD 18669648, 20068231
S242 Phosphorylation HPRD 20068231
T270 Phosphorylation HPRD 20068231
S344 Phosphorylation HPRD 19413330, 17081983, 19664995, ...18452278, 18669648, 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K108 N108 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
Y178 H178 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
Y178 N178 Biomuta DOID:4159 / skin cancer [ cosmic ]
K269 N269 Biomuta DOID:3571 / liver cancer [ cosmic ]
K269 R269 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S283 F283 Biomuta DOID:4159 / skin cancer [ cosmic ]
S357 Y357 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]