iPTMnet Report for Q9NVE7 (PANK4)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9NVE7 / PANK4_HUMAN
Protein Name 4'-phosphopantetheine phosphatase
Gene Name Name: PANK4
Organism Homo sapiens (Human)

PRO ID PR:Q9NVE7
DAG View
PRO Name 4'-phosphopantetheine phosphatase (human)
Definition A 4'-phosphopantetheine phosphatase that is encoded in the genome of human.
Short Label hPANK4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9NVE7 (PANK4) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330
S19 Phosphorylation PhosphoSitePlus
K35 Ubiquitination PhosphoSitePlus
Y51 Phosphorylation PhosphoSitePlus
S63 Phosphorylation PhosphoSitePlus
K69 Ubiquitination PhosphoSitePlus
T71 Phosphorylation PhosphoSitePlus
K118 Ubiquitination PhosphoSitePlus
T123 Phosphorylation PhosphoSitePlus
K129 Ubiquitination PhosphoSitePlus
K131 Ubiquitination PhosphoSitePlus
K137 Ubiquitination PhosphoSitePlus
K141 Ubiquitination PhosphoSitePlus
K144 Ubiquitination PhosphoSitePlus
K153 Ubiquitination PhosphoSitePlus
K160 Ubiquitination PhosphoSitePlus
K171 Ubiquitination PhosphoSitePlus
K234 Ubiquitination PhosphoSitePlus
K278 Ubiquitination PhosphoSitePlus
S279 Phosphorylation PhosphoSitePlus
K288 Ubiquitination PhosphoSitePlus
S393 Phosphorylation PhosphoSitePlus   UniProt 23186163
S404 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
T406 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
K446 Ubiquitination PhosphoSitePlus
K487 Ubiquitination PhosphoSitePlus
K559 Ubiquitination PhosphoSitePlus
K590 Ubiquitination PhosphoSitePlus
K707 Ubiquitination PhosphoSitePlus
C740 Methylation IEDB 31844290


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K35 E35 Biomuta DOID:1324 / lung cancer [ icgc ]
K153 E153 Biomuta DOID:1319 / brain cancer [ icgc ]