iPTMnet Report for Q9NV58 (RNF19A)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9NV58 / RN19A_HUMAN
Protein Name E3 ubiquitin-protein ligase RNF19A
Gene Name Name: RNF19A
Synonyms:RNF19;
Organism Homo sapiens (Human)

PRO ID PR:Q9NV58
DAG View
PRO Name E3 ubiquitin-protein ligase RNF19A (human)
Definition An E3 ubiquitin-protein ligase RNF19A that is encoded in the genome of human.
Short Label hRNF19A
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9NV58 (RNF19A) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S40 Phosphorylation PhosphoSitePlus
S49 Phosphorylation PhosphoSitePlus
S55 Phosphorylation PhosphoSitePlus
S66 Phosphorylation PhosphoSitePlus
S69 Phosphorylation PhosphoSitePlus
C216 Methylation IEDB 31844290
S274 Phosphorylation PhosphoSitePlus
S282 Phosphorylation PhosphoSitePlus
S284 Phosphorylation phospho.ELM   PhosphoSitePlus 17525332
S286 Phosphorylation PhosphoSitePlus
S288 Phosphorylation phospho.ELM   PhosphoSitePlus 17525332
S291 Phosphorylation PhosphoSitePlus
K352 Ubiquitination PhosphoSitePlus
K353 Ubiquitination PhosphoSitePlus
K468 Ubiquitination PhosphoSitePlus
S516 Phosphorylation PhosphoSitePlus
S518 Phosphorylation PhosphoSitePlus
S599 Phosphorylation PhosphoSitePlus
Y604 Phosphorylation PhosphoSitePlus
S631 Phosphorylation PhosphoSitePlus   UniProt 21406692, 24275569
S649 Phosphorylation PhosphoSitePlus
K657 Ubiquitination PhosphoSitePlus
Y750 Phosphorylation PhosphoSitePlus
Y811 Phosphorylation PhosphoSitePlus
T827 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S284 Phosphorylation HPRD 17525332
S288 Phosphorylation HPRD 17525332
S518 Phosphorylation HPRD 20068231
S631 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S66 L66 Biomuta [ cosmic ] DOID:4159 / skin cancer [ cosmic, icgc ]
S69 F69 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S288 R288 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S291 Y291 Biomuta DOID:1319 / brain cancer [ icgc ]
S516 R516 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S518 R518 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
Y811 C811 Biomuta DOID:1324 / lung cancer [ cosmic ]