iPTMnet Report for Q9NV35 (NUDT15)
Protein Information
| UniProt AC / UniProt ID | Q9NV35 / NUD15_HUMAN |
| Protein Name | Nucleotide triphosphate diphosphatase NUDT15 |
| Gene Name | Name: NUDT15 Synonyms:MTH2; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9NV35 |
| PRO Name | nucleotide triphosphate diphosphatase NUDT15 (human) |
| Definition | A nucleotide triphosphate diphosphatase that is encoded in the genome of human. |
| Short Label | hNUDT15 |
| Category | organism-gene |
DAG ViewQ9NV35 (NUDT15) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| R8 | Methylation | score1 | PhosphoSitePlus | |||
| S22 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S42 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y90 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T94 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K110 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K150 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K160 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| R8 | P8 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
| S42 | T42 | Biomuta | DOID:5041 / esophageal cancer [ cosmic ] | |
| T94 | I94 | Biomuta | DOID:363 / uterine cancer [ cosmic ] | |
| K110 | N110 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] |
