iPTMnet Report for Q9NUY8 (TBC1D23)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9NUY8 / TBC23_HUMAN
Protein Name TBC1 domain family member 23
Gene Name Name: TBC1D23
Synonyms:NS4ATP1;
Organism Homo sapiens (Human)

PRO ID PR:Q9NUY8
DAG View
PRO Name TBC1 domain family member 23 (human)
Definition A TBC1 domain family member 23 that is encoded in the genome of human.
Short Label hTBC1D23
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9NUY8 (TBC1D23) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K84 Ubiquitination PhosphoSitePlus
C148 Methylation IEDB 31844290
S300 Phosphorylation PhosphoSitePlus   UniProt 23186163
T301 Phosphorylation PhosphoSitePlus
S378 Phosphorylation PhosphoSitePlus
K384 Ubiquitination PhosphoSitePlus
S465 Phosphorylation PhosphoSitePlus
S466 Phosphorylation PhosphoSitePlus
S469 Phosphorylation PhosphoSitePlus
S474 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 16964243
S478 Phosphorylation PhosphoSitePlus
S485 Phosphorylation PhosphoSitePlus
K489 Ubiquitination PhosphoSitePlus
K495 Ubiquitination PhosphoSitePlus
K497 Acetylation PhosphoSitePlus
K504 Acetylation PhosphoSitePlus
K504 Ubiquitination PhosphoSitePlus
S507 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
T514 Phosphorylation neXtProt   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 22028470, 16964243
T514 Phosphorylation P28482 (MAPK1) neXtProt 22028470
S520 Phosphorylation PhosphoSitePlus   UniProt 23186163
T531 Phosphorylation PhosphoSitePlus
S536 Phosphorylation PhosphoSitePlus
T562 Phosphorylation PhosphoSitePlus
S567 Phosphorylation PhosphoSitePlus
S571 Phosphorylation PhosphoSitePlus   UniProt 24275569
T583 Phosphorylation PhosphoSitePlus
K587 Ubiquitination PhosphoSitePlus
K597 Ubiquitination PhosphoSitePlus
K627 Ubiquitination PhosphoSitePlus
S634 Phosphorylation PhosphoSitePlus
K648 Ubiquitination PhosphoSitePlus
K649 Ubiquitination PhosphoSitePlus
S664 Phosphorylation PhosphoSitePlus
Y674 Phosphorylation PhosphoSitePlus
K684 Ubiquitination PhosphoSitePlus
S699 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S474 Phosphorylation HPRD 19413330, 16964243, 20068231
S507 Phosphorylation HPRD 18669648, 20058876
T514 Phosphorylation HPRD 18669648, 16964243
S552 Phosphorylation HPRD 20166139


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S300 T300 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S465 N465 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S465 I465 Biomuta DOID:3571 / liver cancer [ cosmic ]
K495 E495 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S571 T571 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K649 N649 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K684 * Biomuta DOID:1324 / lung cancer [ cosmic ]