iPTMnet Report for Q9NUT2 (ABCB8)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9NUT2 / MITOS_HUMAN
Protein Name Mitochondrial potassium channel ATP-binding subunit precursor
Gene Name Name: ABCB8
Synonyms:MABC1;
Organism Homo sapiens (Human)

PRO ID PR:Q9NUT2
DAG View
PRO Name mitochondrial potassium channel ATP-binding subunit (human)
Definition A mitochondrial potassium channel ATP-binding subunit that is encoded in the genome of human.
Short Label hABCB8
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9NUT2 (ABCB8) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S84 Phosphorylation PhosphoSitePlus
S86 Phosphorylation PhosphoSitePlus
S102 Phosphorylation PhosphoSitePlus
S233 Phosphorylation PhosphoSitePlus
K247 Ubiquitination PhosphoSitePlus
T257 Phosphorylation PhosphoSitePlus
K263 Ubiquitination PhosphoSitePlus
S271 Phosphorylation PhosphoSitePlus
S276 Phosphorylation PhosphoSitePlus
T295 Phosphorylation PhosphoSitePlus
T310 Phosphorylation PhosphoSitePlus
S314 Phosphorylation PhosphoSitePlus
S429 Phosphorylation PhosphoSitePlus
K465 Ubiquitination PhosphoSitePlus
K513 Ubiquitination PhosphoSitePlus
T514 O-Glycosylation GlyGen 30379171
T540 Phosphorylation PhosphoSitePlus
S544 Phosphorylation PhosphoSitePlus
K573 Ubiquitination PhosphoSitePlus
S577 Phosphorylation PhosphoSitePlus
K617 Ubiquitination PhosphoSitePlus
K628 Ubiquitination PhosphoSitePlus
K699 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S86 C86 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
T257 S257 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K263 T263 Biomuta DOID:1612 / breast cancer [ icgc ]
T295 M295 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:9256 / colorectal cancer [ cosmic ]
S429 F429 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
K513 N513 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
T540 P540 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S544 F544 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]