iPTMnet Report for Q9NUP7 (TRMT13)
Protein Information
| UniProt AC / UniProt ID | Q9NUP7 / TRM13_HUMAN |
| Protein Name | tRNA:m(4)X modification enzyme TRM13 homolog |
| Gene Name | Name: TRMT13 Synonyms:CCDC76; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9NUP7 |
| PRO Name | tRNA:m(4)X modification enzyme TRM13 homolog (human) |
| Definition | A tRNA guanosine-2'-O-methyltransferase TRM13 that is encoded in the genome of human. |
| Short Label | hTRMT13 |
| Category | organism-gene |
Q9NUP7 (TRMT13) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| A2 | Acetylation | score1 | UniProt | 19413330, 22223895, 20068231 | ||
| S7 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S130 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K138 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K165 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K178 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K257 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S368 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S369 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T372 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T387 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S397 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y405 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| A2 | E2 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| K138 | * | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S397 | R397 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| S397 | N397 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] |
DAG View