Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9NU22 / MDN1_HUMAN
Protein Name Midasin
Gene Name Name: MDN1
Synonyms:KIAA0301;
Organism Homo sapiens (Human)

PRO ID PR:Q9NU22
DAG View
PRO Name midasin (human)
Definition A midasin that is encoded in the genome of human.
Short Label hMDN1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9NU22 (MDN1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 19413330
K19 Ubiquitination PhosphoSitePlus
K33 Ubiquitination PhosphoSitePlus
K81 Ubiquitination PhosphoSitePlus
K100 Ubiquitination PhosphoSitePlus
K117 Ubiquitination PhosphoSitePlus
Y186 Phosphorylation PhosphoSitePlus
K208 Ubiquitination PhosphoSitePlus
S243 Phosphorylation PhosphoSitePlus
K249 Ubiquitination PhosphoSitePlus
S321 Phosphorylation PhosphoSitePlus
K350 Ubiquitination PhosphoSitePlus
K356 Ubiquitination PhosphoSitePlus
K366 Ubiquitination PhosphoSitePlus
Y372 Phosphorylation PhosphoSitePlus
K433 Ubiquitination PhosphoSitePlus
K466 Ubiquitination PhosphoSitePlus
K478 Ubiquitination PhosphoSitePlus
T539 Phosphorylation PhosphoSitePlus
K592 Ubiquitination PhosphoSitePlus
S599 Phosphorylation PhosphoSitePlus
K600 Ubiquitination PhosphoSitePlus
N602 N-Glycosylation GlyGen 30237853
S604 Phosphorylation HPRD   PhosphoSitePlus 20068231
K636 Ubiquitination PhosphoSitePlus
T649 Phosphorylation PhosphoSitePlus
T653 Phosphorylation PhosphoSitePlus
K683 Ubiquitination PhosphoSitePlus
K717 Ubiquitination PhosphoSitePlus
K722 Ubiquitination PhosphoSitePlus
K773 Ubiquitination PhosphoSitePlus
K778 Ubiquitination PhosphoSitePlus
K781 Methylation PhosphoSitePlus
K781 Ubiquitination PhosphoSitePlus
K790 Ubiquitination PhosphoSitePlus
K792 Ubiquitination PhosphoSitePlus
K891 Ubiquitination PhosphoSitePlus
K931 Ubiquitination PhosphoSitePlus
K1008 Ubiquitination PhosphoSitePlus
K1020 Ubiquitination PhosphoSitePlus
K1024 Ubiquitination PhosphoSitePlus
K1031 Ubiquitination PhosphoSitePlus
T1177 Phosphorylation PhosphoSitePlus   UniProt 21406692
K1184 Ubiquitination PhosphoSitePlus
K1234 Ubiquitination PhosphoSitePlus
S1237 Phosphorylation PhosphoSitePlus
Y1242 Phosphorylation PhosphoSitePlus
K1248 Ubiquitination PhosphoSitePlus
K1266 Ubiquitination PhosphoSitePlus
T1288 Phosphorylation PhosphoSitePlus
Y1292 Phosphorylation PhosphoSitePlus
Y1303 Phosphorylation PhosphoSitePlus
K1312 Ubiquitination PhosphoSitePlus
K1325 Ubiquitination PhosphoSitePlus
K1330 Ubiquitination PhosphoSitePlus
K1339 Ubiquitination PhosphoSitePlus
K1344 Ubiquitination PhosphoSitePlus
T1392 Phosphorylation PhosphoSitePlus
K1439 Ubiquitination PhosphoSitePlus
S1445 Phosphorylation HPRD 20068231
K1489 Ubiquitination PhosphoSitePlus
S1490 Phosphorylation PhosphoSitePlus
K1496 Ubiquitination PhosphoSitePlus
K1502 Ubiquitination PhosphoSitePlus
K1513 Ubiquitination PhosphoSitePlus
T1520 Phosphorylation PhosphoSitePlus
K1529 Ubiquitination PhosphoSitePlus
K1530 Ubiquitination PhosphoSitePlus
S1533 Phosphorylation PhosphoSitePlus
K1597 Ubiquitination PhosphoSitePlus
S1607 Phosphorylation HPRD   PhosphoSitePlus 20068231
K1683 Acetylation PhosphoSitePlus   UniProt 19608861
K1683 Ubiquitination PhosphoSitePlus
K1687 Ubiquitination PhosphoSitePlus
K1695 Ubiquitination PhosphoSitePlus
K1746 Ubiquitination PhosphoSitePlus
K1747 Ubiquitination PhosphoSitePlus
S1754 Phosphorylation PhosphoSitePlus   UniProt 23186163
K1759 Ubiquitination PhosphoSitePlus
K1768 Ubiquitination PhosphoSitePlus
T1773 Phosphorylation PhosphoSitePlus
K1799 Ubiquitination PhosphoSitePlus
K1863 Ubiquitination PhosphoSitePlus
K1940 Ubiquitination PhosphoSitePlus
K1989 Ubiquitination PhosphoSitePlus
K1995 Ubiquitination PhosphoSitePlus
Y2022 Phosphorylation PhosphoSitePlus
S2023 Phosphorylation PhosphoSitePlus
K2120 Ubiquitination PhosphoSitePlus
K2193 Ubiquitination PhosphoSitePlus
K2198 Ubiquitination PhosphoSitePlus
K2234 Acetylation PhosphoSitePlus
T2266 Phosphorylation HPRD 20068231
K2406 Ubiquitination PhosphoSitePlus
K2414 Ubiquitination PhosphoSitePlus
K2471 Ubiquitination PhosphoSitePlus
K2488 Ubiquitination PhosphoSitePlus
S2492 Phosphorylation PhosphoSitePlus
K2656 Ubiquitination PhosphoSitePlus
K2772 Ubiquitination PhosphoSitePlus
K2796 Ubiquitination PhosphoSitePlus
K2825 Ubiquitination PhosphoSitePlus
K2858 Ubiquitination PhosphoSitePlus
S2860 Phosphorylation PhosphoSitePlus
S2878 Phosphorylation PhosphoSitePlus
K2896 Ubiquitination PhosphoSitePlus
K2905 Ubiquitination PhosphoSitePlus
K2906 Ubiquitination PhosphoSitePlus
K3056 Methylation PhosphoSitePlus
K3056 Ubiquitination PhosphoSitePlus
S3112 Phosphorylation PhosphoSitePlus
S3113 Phosphorylation PhosphoSitePlus
K3211 Ubiquitination PhosphoSitePlus
K3246 Ubiquitination PhosphoSitePlus
K3250 Ubiquitination PhosphoSitePlus
K3255 Ubiquitination PhosphoSitePlus
K3266 Ubiquitination PhosphoSitePlus
S3272 Phosphorylation PhosphoSitePlus
T3276 Phosphorylation PhosphoSitePlus
K3312 Acetylation PhosphoSitePlus
S3361 Phosphorylation HPRD   PhosphoSitePlus 20068231
S3367 Phosphorylation HPRD   PhosphoSitePlus 20068231
K3370 Ubiquitination PhosphoSitePlus
T3434 Phosphorylation PhosphoSitePlus
S3444 Phosphorylation PhosphoSitePlus
R3469 Methylation PhosphoSitePlus
K3473 Ubiquitination PhosphoSitePlus
K3482 Acetylation PhosphoSitePlus
K3482 Ubiquitination PhosphoSitePlus
K3513 Ubiquitination PhosphoSitePlus
K3545 Ubiquitination PhosphoSitePlus
S3550 Phosphorylation PhosphoSitePlus
Y3553 Phosphorylation PhosphoSitePlus
S3565 Phosphorylation PhosphoSitePlus
K3576 Ubiquitination PhosphoSitePlus
K3583 Ubiquitination PhosphoSitePlus
S3768 Phosphorylation PhosphoSitePlus
Y3919 Phosphorylation PhosphoSitePlus
Y3920 Phosphorylation PhosphoSitePlus
K3940 Ubiquitination PhosphoSitePlus
K3943 Ubiquitination PhosphoSitePlus
K3947 Ubiquitination PhosphoSitePlus
K3950 Ubiquitination PhosphoSitePlus
K3960 Ubiquitination PhosphoSitePlus
K3972 Ubiquitination PhosphoSitePlus
K3976 Ubiquitination PhosphoSitePlus
S3992 Phosphorylation PhosphoSitePlus
K3994 Ubiquitination PhosphoSitePlus
K4066 Ubiquitination PhosphoSitePlus
S4075 Phosphorylation PhosphoSitePlus
K4102 Ubiquitination PhosphoSitePlus
K4117 Ubiquitination PhosphoSitePlus
K4123 Ubiquitination PhosphoSitePlus
S4128 Phosphorylation PhosphoSitePlus
K4132 Ubiquitination PhosphoSitePlus
K4136 Ubiquitination PhosphoSitePlus
K4143 Ubiquitination PhosphoSitePlus
K4194 Ubiquitination PhosphoSitePlus
T4212 Phosphorylation HPRD   PhosphoSitePlus   UniProt 23186163, 20068231
K4215 Ubiquitination PhosphoSitePlus
S4258 Phosphorylation PhosphoSitePlus
K4375 Ubiquitination PhosphoSitePlus
T4388 Phosphorylation HPRD   PhosphoSitePlus 18491316
K4392 Ubiquitination PhosphoSitePlus
T4393 Phosphorylation PhosphoSitePlus
T4396 Phosphorylation HPRD   PhosphoSitePlus 18491316
T4534 Phosphorylation PhosphoSitePlus
S4538 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18691976, 21406692, 23186163, ...19369195, 15302935, 19664994, 19664995, 18452278, 19651622, 18669648, 19690332, 20068231, 19691289
Y4543 Phosphorylation PhosphoSitePlus
S4615 Phosphorylation PhosphoSitePlus
Y4617 Phosphorylation PhosphoSitePlus
S4618 Phosphorylation PhosphoSitePlus
S4664 Phosphorylation PhosphoSitePlus
T4670 Phosphorylation PhosphoSitePlus
Y4675 Phosphorylation PhosphoSitePlus
S4690 Phosphorylation PhosphoSitePlus
K4705 Ubiquitination PhosphoSitePlus
S4730 Phosphorylation PhosphoSitePlus
S4752 Phosphorylation HPRD   PhosphoSitePlus   UniProt 21406692, 23186163, 17081983, ...18452278, 19651622, 19690332, 20068231
S4754 Phosphorylation HPRD   PhosphoSitePlus   UniProt 21406692, 23186163, 17081983, ...18452278, 19651622, 20068231
S4807 Phosphorylation PhosphoSitePlus
R4856 Methylation PhosphoSitePlus
Y4858 Phosphorylation PhosphoSitePlus
S4889 Phosphorylation HPRD   PhosphoSitePlus   UniProt 21406692, 18452278
T4898 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 18691976, 21406692, ...23186163, 17081983, 15302935, 18452278, 19651622, 18669648, 20068231
S4937 Phosphorylation HPRD   PhosphoSitePlus   UniProt 21406692, 18452278
S4946 Phosphorylation PhosphoSitePlus   UniProt 21406692
S5015 Phosphorylation HPRD   PhosphoSitePlus   UniProt 21406692, 23186163, 17081983, ...19664994, 18452278, 20068231
T5017 Phosphorylation PhosphoSitePlus
T5094 Phosphorylation PhosphoSitePlus
S5096 Phosphorylation PhosphoSitePlus
T5123 Phosphorylation PhosphoSitePlus
T5126 Phosphorylation PhosphoSitePlus
S5128 Phosphorylation PhosphoSitePlus
Y5158 Phosphorylation PhosphoSitePlus
Y5163 Phosphorylation PhosphoSitePlus
K5253 Ubiquitination PhosphoSitePlus
R5285 Methylation PhosphoSitePlus
R5290 Methylation PhosphoSitePlus
T5338 Phosphorylation PhosphoSitePlus
K5342 Ubiquitination PhosphoSitePlus
K5357 Ubiquitination PhosphoSitePlus
K5455 Ubiquitination PhosphoSitePlus
K5506 Ubiquitination PhosphoSitePlus
K5541 Ubiquitination PhosphoSitePlus
K5546 Methylation PhosphoSitePlus
K5546 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K19 N19 Biomuta DOID:363 / uterine cancer [ tcga ]
K100 E100 Biomuta DOID:10283 / prostate cancer [ cosmic ]
T539 N539 Biomuta DOID:3571 / liver cancer [ icgc ]
T539 A539 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc, tcga ]
S599 R599 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
K717 T717 Biomuta DOID:11934 / head and neck cancer [ tcga ]
K778 M778 Biomuta DOID:1324 / lung cancer [ cosmic, icgc, tcga ]
K931 N931 Biomuta DOID:1909 / melanoma [ cosmic ]
K1008 N1008 Biomuta DOID:1793 / pancreatic cancer [ tcga ]
K1031 N1031 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc, tcga ]
S1490 Y1490 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
S1490 F1490 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ] DOID:1909 / melanoma [ cosmic ]
K1496 Q1496 Biomuta DOID:363 / uterine cancer [ tcga ]
K1496 N1496 Biomuta DOID:4362 / cervical cancer [ tcga ]
K1513 E1513 Biomuta DOID:1115 / sarcoma [ tcga ]
T1520 N1520 Biomuta DOID:3571 / liver cancer [ icgc ]
K1597 N1597 Biomuta DOID:1324 / lung cancer [ cosmic, icgc, tcga ]
K1683 N1683 Biomuta DOID:1612 / breast cancer [ tcga ]
K1687 N1687 Biomuta DOID:5041 / esophageal cancer [ tcga ]
K1768 N1768 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc, tcga ]
K1989 Q1989 Biomuta DOID:363 / uterine cancer [ tcga ]
Y2022 C2022 Biomuta DOID:9256 / colorectal cancer [ tcga ]
K2234 R2234 Biomuta DOID:1324 / lung cancer [ cosmic ]
S3113 L3113 Biomuta DOID:363 / uterine cancer [ tcga ] DOID:9256 / colorectal cancer [ icgc, tcga ] DOID:1909 / melanoma [ tcga ] DOID:3070 / malignant glioma [ tcga ]
K3255 E3255 Biomuta DOID:1909 / melanoma [ cosmic ]
S3361 C3361 Biomuta DOID:5041 / esophageal cancer [ tcga ]
S3444 * Biomuta DOID:263 / kidney cancer [ cosmic ]
S3444 L3444 Biomuta DOID:4362 / cervical cancer [ tcga ] DOID:0070003 / blastoma [ cosmic ]
R3469 * Biomuta DOID:10283 / prostate cancer [ cosmic ]
Y3920 C3920 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc, tcga ]
K3947 E3947 Biomuta DOID:9256 / colorectal cancer [ tcga ]
K3972 T3972 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
K3994 Q3994 Biomuta DOID:263 / kidney cancer [ cosmic, icgc, tcga ]
S4075 R4075 Biomuta DOID:3571 / liver cancer [ icgc ]
T4534 S4534 Biomuta DOID:1324 / lung cancer [ icgc ]
Y4617 D4617 Biomuta DOID:5041 / esophageal cancer [ icgc ]
S4730 L4730 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
T4898 A4898 Biomuta DOID:3571 / liver cancer [ icgc, tcga ] DOID:0070003 / blastoma [ cosmic ]
T5017 K5017 Biomuta DOID:3571 / liver cancer [ icgc ]
T5017 S5017 Biomuta DOID:10534 / stomach cancer [ cosmic ]
T5126 M5126 Biomuta DOID:9256 / colorectal cancer [ icgc ]