iPTMnet Report for Q9NU19 (TBC1D22B)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9NU19 / TB22B_HUMAN
Protein Name TBC1 domain family member 22B
Gene Name Name: TBC1D22B
Synonyms:C6orf197;
Organism Homo sapiens (Human)

PRO ID PR:Q9NU19
DAG View
PRO Name TBC1 domain family member 22B (human)
Definition A TBC1 domain family member 22B that is encoded in the genome of human.
Short Label hTBC1D22B
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9NU19 (TBC1D22B) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 23572552
S13 Phosphorylation PhosphoSitePlus
S58 Phosphorylation PhosphoSitePlus   UniProt 23186163
S114 Phosphorylation PhosphoSitePlus
S116 Phosphorylation PhosphoSitePlus   UniProt 23186163
T117 Phosphorylation PhosphoSitePlus
T118 Phosphorylation PhosphoSitePlus
S119 Phosphorylation PhosphoSitePlus
Y125 Phosphorylation PhosphoSitePlus
K129 Ubiquitination PhosphoSitePlus
S130 Phosphorylation PhosphoSitePlus
S132 Phosphorylation PhosphoSitePlus
S140 Phosphorylation PhosphoSitePlus
S141 Phosphorylation PhosphoSitePlus
T143 Phosphorylation PhosphoSitePlus
S154 Phosphorylation PhosphoSitePlus   UniProt 23186163, 23572552
S168 Phosphorylation PhosphoSitePlus
T219 Phosphorylation PhosphoSitePlus
K375 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T117 M117 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ]
T118 A118 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S119 P119 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T143 A143 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S168 L168 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ]
T219 I219 Biomuta DOID:4159 / skin cancer [ cosmic ]