iPTMnet Report for Q9NSY1 (BMP2K)
Protein Information
| UniProt AC / UniProt ID | Q9NSY1 / BMP2K_HUMAN |
| Protein Name | BMP-2-inducible protein kinase |
| Gene Name | Name: BMP2K Synonyms:BIKE;ORFNames:HRIHFB2017; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9NSY1 |
| PRO Name | BMP-2-inducible protein kinase (human) |
| Definition | A BMP-2-inducible protein kinase that is encoded in the genome of human. |
| Short Label | hBMP2K |
| Category | organism-gene |
Q9NSY1 (BMP2K) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S14 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 19369195, 24275569 | ||
| K93 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K173 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K182 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K211 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K222 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K223 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K241 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y257 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S367 | O-Glycosylation | score1 | GlyGen | 34019948, 30620550, 35132862, ... | ||
| S378 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T381 | O-Glycosylation | score1 | GlyGen | 32938750 | ||
| T383 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T394 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y594 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K613 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S616 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S665 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S680 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S689 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| S715 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S728 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S740 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S742 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| S791 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y813 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S817 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| S818 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| Y820 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S824 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S826 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T829 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T834 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 18691976 | ||
| S843 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S928 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T935 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S945 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S947 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S949 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S974 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S979 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S980 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K991 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T1002 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T1011 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y1012 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T1014 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1029 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163, 19690332, 20068231 | ||
| S1031 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1032 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163, 19690332 | ||
| T1037 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1039 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
| S1041 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| S1046 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1076 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 18691976 | ||
| S1080 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1089 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T1097 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1107 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 19369195, 23186163, 17081983, ... | ||
| S1111 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163, 20068231 | ||
| S1114 | Phosphorylation | score1 | PhosphoSitePlus |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S10 | Phosphorylation | score0 | HPRD | 18691976 | ||
| Y257 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S680 | Phosphorylation | score0 | HPRD | 18691976 | ||
| S685 | Phosphorylation | score0 | HPRD | 18691976 | ||
| S687 | Phosphorylation | score0 | HPRD | 18691976 | ||
| S689 | Phosphorylation | score0 | HPRD | 19651622, 20068231 | ||
| S697 | Phosphorylation | score0 | HPRD | 18691976 | ||
| T727 | Phosphorylation | score0 | HPRD | 18691976 | ||
| S824 | Phosphorylation | score0 | HPRD | 18691976 | ||
| S826 | Phosphorylation | score0 | HPRD | 18691976 | ||
| T834 | Phosphorylation | score0 | HPRD | 18691976 | ||
| S947 | Phosphorylation | score0 | HPRD | 19413330, 18691976 | ||
| S949 | Phosphorylation | score0 | HPRD | 18452278 | ||
| T963 | Phosphorylation | score0 | HPRD | 19651622 | ||
| S965 | Phosphorylation | score0 | HPRD | 19651622 | ||
| S979 | Phosphorylation | score0 | HPRD | 18691976 | ||
| T1002 | Phosphorylation | score0 | HPRD | 18691976 | ||
| S1003 | Phosphorylation | score0 | HPRD | 18691976 | ||
| T1011 | Phosphorylation | score0 | HPRD | 18691976 | ||
| S1029 | Phosphorylation | score0 | HPRD | 19651622, 18691976, 20068231 | ||
| S1031 | Phosphorylation | score0 | HPRD | 19651622, 18691976, 20068231 | ||
| S1032 | Phosphorylation | score0 | HPRD | 19651622, 18691976, 20068231 | ||
| S1041 | Phosphorylation | score0 | HPRD | 18691976 | ||
| S1076 | Phosphorylation | score0 | HPRD | 18691976 | ||
| S1107 | Phosphorylation | score0 | HPRD | 18691976, 17081983, 20068231 | ||
| S1111 | Phosphorylation | score0 | HPRD | 18691976, 20068231 |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S10 | Phosphorylation | score0 | HPRD | 18691976 | ||
| Y257 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S651 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K656 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| Y257 | D257 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
| K656 | N656 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] |
DAG View