iPTMnet Report for Q9NSU2 (TREX1)
Protein Information
UniProt AC / UniProt ID | Q9NSU2 / TREX1_HUMAN |
Protein Name | Three-prime repair exonuclease 1 |
Gene Name | Name: TREX1 |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9NSU2 |
PRO Name | three-prime repair exonuclease 1 (human) |
Definition | A three-prime repair exonuclease 1 that is encoded in the genome of human. |
Short Label | hTREX1 |
Category | organism-gene |
Q9NSU2 (TREX1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S78 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 18669648 | ||
C120 | Methylation | score1 | IEDB | 31844290 | ||
S167 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
K175 | Ubiquitination | score1 | PhosphoSitePlus | |||
S178 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y183 | Phosphorylation | score1 | PhosphoSitePlus | |||
S261 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 18669648, 23186163 | ||
S263 | Phosphorylation | score1 | PhosphoSitePlus | |||
K277 | Methylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S78 | I78 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
K175 | N175 | Biomuta | DOID:4159 / skin cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic ] |