iPTMnet Report for Q9NSG2 (FIRRM)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9NSG2 / FIRRM_HUMAN
Protein Name FIGNL1-interacting regulator of recombination and mitosis
Gene Name Name: FIRRM
Synonyms:APOLO1;
Organism Homo sapiens (Human)

PRO ID PR:Q9NSG2
DAG View
PRO Name uncharacterized protein C1orf112 (human)
Definition An uncharacterized protein C1orf112 that is encoded in the genome of human.
Short Label hC1orf112
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9NSG2 (FIRRM) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K25 Ubiquitination PhosphoSitePlus
S42 Phosphorylation HPRD 20068231
S43 Phosphorylation PhosphoSitePlus   UniProt 34260926, 23186163
C113 Methylation IEDB 31844290
K188 Ubiquitination PhosphoSitePlus
K192 Ubiquitination PhosphoSitePlus
K198 Ubiquitination PhosphoSitePlus
K244 Ubiquitination PhosphoSitePlus
S288 Phosphorylation PhosphoSitePlus
Y290 Phosphorylation PhosphoSitePlus
T292 Phosphorylation PhosphoSitePlus
K523 Ubiquitination PhosphoSitePlus
S744 Phosphorylation PhosphoSitePlus   UniProt 34260926
K748 Ubiquitination PhosphoSitePlus
K759 Ubiquitination PhosphoSitePlus
K767 Ubiquitination PhosphoSitePlus
K783 Ubiquitination PhosphoSitePlus
K792 Acetylation PhosphoSitePlus   UniProt 19608861
K792 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K192 * Biomuta DOID:1324 / lung cancer [ cosmic ]
K198 N198 Biomuta DOID:363 / uterine cancer [ icgc ]
K748 N748 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic ]
K767 N767 Biomuta DOID:9256 / colorectal cancer [ cosmic ]