iPTMnet Report for Q9NRW7 (VPS45)
Protein Information
| UniProt AC / UniProt ID | Q9NRW7 / VPS45_HUMAN |
| Protein Name | Vacuolar protein sorting-associated protein 45 |
| Gene Name | Name: VPS45 Synonyms:VPS45A,VPS45B; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9NRW7 |
| PRO Name | vacuolar protein sorting-associated protein 45 (human) |
| Definition | A vacuolar protein sorting-associated protein 45 that is encoded in the genome of human. |
| Short Label | hVPS45 |
| Category | organism-gene |
DAG ViewQ9NRW7 (VPS45) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| Y10 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K76 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y81 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S168 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K185 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K192 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K197 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K257 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y272 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K296 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K304 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S307 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163, 24275569 | ||
| K312 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y318 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K322 | Methylation | score1 | PhosphoSitePlus | |||
| K322 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K323 | Methylation | score1 | PhosphoSitePlus | |||
| T327 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K330 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S339 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K371 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K378 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K418 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S424 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K432 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S437 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S441 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K443 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K450 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K454 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K457 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K479 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K483 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y487 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K557 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S559 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S560 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T563 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S564 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| Y10 | H10 | Biomuta | [ cosmic ] | |
| Y10 | C10 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| K76 | N76 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| K312 | M312 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| S339 | P339 | Biomuta | DOID:363 / uterine cancer [ cosmic ] | |
| K432 | E432 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| S441 | R441 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] | |
| K457 | T457 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
| Y487 | F487 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
| S564 | * | Biomuta | DOID:4159 / skin cancer [ cosmic ] |
