iPTMnet Report for Q9NRW4 (DUSP22)
Protein Information
| UniProt AC / UniProt ID | Q9NRW4 / DUS22_HUMAN |
| Protein Name | Dual specificity protein phosphatase 22 |
| Gene Name | Name: DUSP22 Synonyms:JSP1,LMWDSP2,MKPX; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9NRW4 |
| PRO Name | dual specificity protein phosphatase 22 (human) |
| Definition | A dual specificity protein phosphatase 22 that is encoded in the genome of human. |
| Short Label | hDUSP22 |
| Category | organism-gene |
DAG ViewQ9NRW4 (DUSP22) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| G2 | Myristoylation | score2 | UniProt | 20553486 | ||
| K18 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S36 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S58 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| S60 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K151 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K166 | Ubiquitination | score1 | PhosphoSitePlus |
|
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| T178 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S189 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| G2 | R2 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| G2 | E2 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| S36 | F36 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S36 | C36 | Biomuta | [ cosmic ] DOID:1115 / sarcoma [ icgc ] | |
| S58 | L58 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| S189 | I189 | Biomuta | DOID:363 / uterine cancer [ icgc ] |
