Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9NRR6 / INP5E_HUMAN
Protein Name 72 kDa inositol polyphosphate 5-phosphatase precursor
Gene Name Name: INPP5E
Organism Homo sapiens (Human)

PRO ID PR:Q9NRR6
DAG View
PRO Name 72 kDa inositol polyphosphate 5-phosphatase (human)
Definition A 72 kDa inositol polyphosphate 5-phosphatase that is encoded in the genome of human.
Short Label hINPP5E
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9NRR6 (INPP5E) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S38 Phosphorylation PhosphoSitePlus
S85 Phosphorylation PhosphoSitePlus
S99 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 17525332, 23186163
T109 Phosphorylation phospho.ELM   PhosphoSitePlus 17287340
S153 Phosphorylation PhosphoSitePlus
S156 Phosphorylation PhosphoSitePlus
S166 Phosphorylation PhosphoSitePlus
K220 Ubiquitination PhosphoSitePlus
S232 Phosphorylation PhosphoSitePlus
S233 Phosphorylation PhosphoSitePlus
S241 Phosphorylation PhosphoSitePlus
K254 Ubiquitination PhosphoSitePlus
S255 Phosphorylation PhosphoSitePlus
Y293 Phosphorylation PhosphoSitePlus
Y439 Phosphorylation PhosphoSitePlus
T455 Phosphorylation PhosphoSitePlus
K521 Ubiquitination PhosphoSitePlus
T542 Phosphorylation PhosphoSitePlus
K565 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S99 Phosphorylation HPRD 17525332
T109 Phosphorylation HPRD 17287340


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S232 R232 Biomuta DOID:263 / kidney cancer [ tcga ]
Y439 * Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]