iPTMnet Report for Q9NRN9 (METTL5)
Protein Information
| UniProt AC / UniProt ID | Q9NRN9 / METL5_HUMAN |
| Protein Name | rRNA N6-adenosine-methyltransferase METTL5 |
| Gene Name | Name: METTL5 ORFNames:DC3,HSPC133; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9NRN9 |
| PRO Name | rRNA N6-adenosine-methyltransferase METTL5 (human) |
| Definition | An rRNA N6-adenosine-methyltransferase METTL5 that is encoded in the genome of human. |
| Short Label | hMETTL5 |
| Category | organism-gene |
DAG ViewQ9NRN9 (METTL5) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| K7 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K21 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K118 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K132 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K135 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K143 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K158 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K175 | Acetylation | score1 | PhosphoSitePlus | |||
| K195 | Acetylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K7 | E7 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
| K21 | R21 | Biomuta | DOID:363 / uterine cancer [ cosmic ] | |
| K143 | N143 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| K158 | R158 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| K175 | N175 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] |
