Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9NRN7 / ADPPT_HUMAN
Protein Name L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase
Gene Name Name: AASDHPPT
ORFNames:CGI-80,HAH-P,HSPC223,x0005;
Organism Homo sapiens (Human)

PRO ID PR:Q9NRN7
DAG View
PRO Name L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase (human)
Definition An L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase that is encoded in the genome of human.
Short Label hAASDHPPT
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9NRN7 (AASDHPPT) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K45 Ubiquitination PhosphoSitePlus
K58 Acetylation PhosphoSitePlus
K58 Ubiquitination PhosphoSitePlus
K74 Ubiquitination PhosphoSitePlus
K89 Acetylation PhosphoSitePlus
K89 Ubiquitination PhosphoSitePlus
K149 Acetylation PhosphoSitePlus
K149 Ubiquitination PhosphoSitePlus
K151 Acetylation PhosphoSitePlus
K151 Ubiquitination PhosphoSitePlus
K155 Ubiquitination PhosphoSitePlus
R161 Methylation PhosphoSitePlus
K164 Ubiquitination PhosphoSitePlus
T168 Phosphorylation PhosphoSitePlus
Y174 Phosphorylation PhosphoSitePlus
K180 Ubiquitination PhosphoSitePlus
K214 Ubiquitination PhosphoSitePlus
K226 Ubiquitination PhosphoSitePlus
S233 Phosphorylation PhosphoSitePlus
S258 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 17525332, 23186163, 18669648, ...20068231
K263 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S233 Phosphorylation HPRD 20068231
S258 Phosphorylation HPRD 19651622, 18077418, 17525332, ...18669648, 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K58 R58 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
K149 Q149 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K151 Q151 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K151 * Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S233 N233 Biomuta DOID:1725 / peritoneum cancer [ cosmic ]