iPTMnet Report for Q9NRD9 (DUOX1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9NRD9 / DUOX1_HUMAN
Protein Name Dual oxidase 1 precursor
Gene Name Name: DUOX1
Synonyms:DUOX,LNOX1,THOX1;
Organism Homo sapiens (Human)

PRO ID PR:Q9NRD9
DAG View
PRO Name dual oxidase 1 (human)
Definition A dual oxidase 1 that is encoded in the genome of human.
Short Label hDUOX1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9NRD9 (DUOX1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S79 Phosphorylation PhosphoSitePlus
S83 Phosphorylation PhosphoSitePlus
S91 Phosphorylation PhosphoSitePlus
S355 Phosphorylation PhosphoSitePlus
S356 Phosphorylation PhosphoSitePlus
S634 Phosphorylation PhosphoSitePlus
S637 Phosphorylation PhosphoSitePlus
S694 Phosphorylation PhosphoSitePlus
S955 Phosphorylation P17612 (PRKACA) neXtProt   PhosphoSitePlus   Signor 19144650
Y956 Phosphorylation PhosphoSitePlus
S958 Phosphorylation PhosphoSitePlus
S965 Phosphorylation PhosphoSitePlus
S1008 Phosphorylation PhosphoSitePlus
Y1064 Phosphorylation PhosphoSitePlus
S1086 Phosphorylation PhosphoSitePlus
S1217 Phosphorylation P17612 (PRKACA) neXtProt   PhosphoSitePlus   Signor 19144650
S1302 O-Glycosylation GlyGen 30620550
S1397 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S1008 Phosphorylation HPRD 18491316


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S83 * Biomuta DOID:2394 / ovarian cancer [ cosmic ]
S91 F91 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S355 * Biomuta DOID:363 / uterine cancer [ cosmic ]
S637 F637 Biomuta DOID:4159 / skin cancer [ cosmic ]
S637 Y637 Biomuta DOID:3571 / liver cancer [ cosmic ]
S694 F694 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
Y1064 C1064 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S1086 L1086 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:4159 / skin cancer [ cosmic ]