iPTMnet Report for Q9NRD5 (PICK1)
Protein Information
| UniProt AC / UniProt ID | Q9NRD5 / PICK1_HUMAN |
| Protein Name | PRKCA-binding protein |
| Gene Name | Name: PICK1 Synonyms:PRKCABP; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9NRD5 |
| PRO Name | PRKCA-binding protein (human) |
| Definition | A PRKCA-binding protein that is encoded in the genome of human. |
| Short Label | hPICK1 |
| Category | organism-gene |
DAG ViewQ9NRD5 (PICK1) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| T18 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S77 | Phosphorylation | score2 | RLIMS-P+ | 22129425 | ||
| S77 | Phosphorylation | P17252 (PRKCA) | score2 | RLIMS-P+ | 22129425 | |
| T82 | Phosphorylation | score4 | RLIMS-P UniProt | 20403402, 17327904 | ||
| K103 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K109 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K151 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K164 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K209 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K219 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S262 | Phosphorylation | score0 | RLIMS-P | 15178939 | ||
| Y285 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y292 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K318 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S339 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S342 | Phosphorylation | score2 | PhosphoSitePlus | 26472923 | ||
| S342 | Phosphorylation | P49841 (GSK3B) | score2 | PhosphoSitePlus | 26472923 | |
| Y349 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T379 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K408 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S411 | Phosphorylation | score1 | PhosphoSitePlus | |||
| C413 | S-Nitrosylation | score0 | dbSNO | 26338901 | ||
| S415 | Phosphorylation | score2 | PhosphoSitePlus | 26472923 | ||
| S415 | Phosphorylation | P49841 (GSK3B) | score2 | PhosphoSitePlus | 26472923 |
PTM-dependent PPI
|
PTM type | Substrate | Site | Interactant | Association type | Source | PMID |
|---|---|---|---|---|---|---|---|
| Phosphorylation | P42262 (GRIA2) | S880 | Q9NRD5 (PICK1) | unknown | eFIP | 22049330 | |
| Phosphorylation | P78348 (ASIC1) | S479 | Q9NRD5 (PICK1) | inhibited_association | eFIP | 12578970 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K164 | I164 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
| K209 | * | Biomuta | DOID:4159 / skin cancer [ cosmic ] |
