Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9NR97 / TLR8_HUMAN
Protein Name Toll-like receptor 8 precursor
Gene Name Name: TLR8
ORFNames:UNQ249/PRO286;
Organism Homo sapiens (Human)

PRO ID PR:Q9NR97
DAG View
PRO Name Toll-like receptor 8 (human)
Definition A Toll-like receptor 8 that is encoded in the genome of human.
Short Label hTLR8
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9NR97 (TLR8) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
N80 N-Glycosylation UniProt 19159218
N88 N-Glycosylation UniProt 19159218
N293 N-Glycosylation UniProt 23520111
S345 Phosphorylation PhosphoSitePlus
Y348 Phosphorylation PhosphoSitePlus
S368 Phosphorylation PhosphoSitePlus
N395 N-Glycosylation UniProt 23520111
N511 N-Glycosylation UniProt 23520111
N546 N-Glycosylation UniProt 23520111
N590 N-Glycosylation UniProt 23520111
N640 N-Glycosylation UniProt 23520111
N680 N-Glycosylation UniProt 23520111
T762 Phosphorylation PhosphoSitePlus
S765 Phosphorylation PhosphoSitePlus
Y880 Phosphorylation PhosphoSitePlus
Y886 Phosphorylation PhosphoSitePlus
S935 Phosphorylation PhosphoSitePlus
S939 Phosphorylation PhosphoSitePlus
Y1030 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y348 C348 Biomuta DOID:363 / uterine cancer [ tcga ]
N640 T640 Biomuta DOID:9256 / colorectal cancer [ tcga ] DOID:1909 / melanoma [ cosmic ]
S765 Y765 Biomuta DOID:363 / uterine cancer [ tcga ] DOID:1324 / lung cancer [ cosmic, icgc, tcga ]