iPTMnet Report for Q9NR96 (TLR9)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9NR96 / TLR9_HUMAN
Protein Name Toll-like receptor 9 precursor
Gene Name Name: TLR9
ORFNames:UNQ5798/PRO19605;
Organism Homo sapiens (Human)

PRO ID PR:Q9NR96
DAG View
PRO Name Toll-like receptor 9 (human)
Definition A Toll-like receptor 9 that is encoded in the genome of human.
Short Label hTLR9
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9NR96 (TLR9) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
N64 N-Glycosylation GlyGen   IEDB 28314751, 24190977
S88 Phosphorylation PhosphoSitePlus
N200 N-Glycosylation GlyGen 24190977
T202 Phosphorylation PhosphoSitePlus
N209 N-Glycosylation GlyGen 24190977
N210 N-Glycosylation GlyGen 24190977
N242 N-Glycosylation GlyGen 24190977
N300 N-Glycosylation GlyGen 24190977
N340 N-Glycosylation GlyGen 24190977
Y345 Phosphorylation PhosphoSitePlus
Y419 Phosphorylation PhosphoSitePlus
S423 Phosphorylation PhosphoSitePlus
N513 N-Glycosylation GlyGen 24190977
T642 Phosphorylation PhosphoSitePlus
T693 Phosphorylation PhosphoSitePlus
N694 N-Glycosylation GlyGen 24190977
S696 Phosphorylation PhosphoSitePlus
N731 N-Glycosylation GlyGen 24190977
K738 Acetylation PhosphoSitePlus
K789 Ubiquitination PhosphoSitePlus
Y888 Phosphorylation RLIMS-P 22174451
S1004 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S88 N88 Biomuta DOID:10534 / stomach cancer [ cosmic ]
N340 T340 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S696 N696 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
N731 T731 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S1004 N1004 Biomuta DOID:4159 / skin cancer [ cosmic ]