iPTMnet Report for Q9NR82 (KCNQ5)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9NR82 / KCNQ5_HUMAN
Protein Name Potassium voltage-gated channel subfamily KQT member 5
Gene Name Name: KCNQ5
Organism Homo sapiens (Human)

PRO ID PR:Q9NR82
DAG View
PRO Name potassium voltage-gated channel subfamily KQT member 5 (human)
Definition A voltage-gated potassium channel subunit KCNQ5 that is encoded in the genome of human.
Short Label hKCNQ5
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9NR82 (KCNQ5) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T67 Phosphorylation PhosphoSitePlus
S78 Phosphorylation PhosphoSitePlus
S88 Phosphorylation P17612 (PRKACA) PhosphoSitePlus   Signor 30061510
Y96 Phosphorylation PhosphoSitePlus
S263 Phosphorylation PhosphoSitePlus
S447 Phosphorylation PhosphoSitePlus
S457 Phosphorylation PhosphoSitePlus
T459 Phosphorylation PhosphoSitePlus
S464 Phosphorylation PhosphoSitePlus
S466 Phosphorylation PhosphoSitePlus
Y500 Phosphorylation PhosphoSitePlus
T581 Phosphorylation PhosphoSitePlus
S618 Phosphorylation PhosphoSitePlus
K619 Ubiquitination PhosphoSitePlus
Y657 Phosphorylation PhosphoSitePlus
S807 Phosphorylation PhosphoSitePlus
S831 Phosphorylation PhosphoSitePlus   UniProt 23186163
Y861 Phosphorylation PhosphoSitePlus
K863 Acetylation PhosphoSitePlus
S902 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S449 Phosphorylation HPRD 18452278
T450 Phosphorylation HPRD 18452278
T459 Phosphorylation HPRD 18452278
Site PTM Type PTM Enzyme Score Source PMID
S411 Phosphorylation PhosphoSitePlus
Y420 Phosphorylation PhosphoSitePlus
T421 Phosphorylation PhosphoSitePlus
S422 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S457 R457 Biomuta DOID:3571 / liver cancer [ cosmic ]
S464 C464 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S807 N807 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S831 Y831 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S831 F831 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]